前列腺病变的直肠超声声像图特点及前列腺癌分期观察指标的相关性分析  

Relationship of image features of transrectal ultrasound of prostate disease and the observation outcome in clinical stages of prostate cancer

作　　者：贺琰[1] 王小燕[1] 凌冰[1] 黄向红[1] 农美芬[1] 廖明珠[1] 董小圆[1] 韦海明[2] 

机构地区：[1]广西壮族自治区人民医院超声科,南宁530021 [2]广西壮族自治区人民医院病理科,南宁530021

出　　处：《中国临床新医学》2015年第5期397-403,共7页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西自然科学基金资助项目(编号:2011GXNSFA018295)

摘　　要：目的系统地观察及探讨经直肠超声(TRUS)及超声引导下穿刺对前列腺肿大病变患者超声图像特征及前列腺癌(PCa)的前列腺特异性抗原(PSA)及临床分期超声表现特征。方法应用经直肠彩色多普勒超声对临床拟诊为PCa患者进行检查,然后经直肠超声引导下前列腺穿刺,方法为系统6点加可疑结节处穿刺法;与血清PSA及病理结果对照;并将前列腺癌血清PSA、穿刺活检阳性百分数(PPBCs)、Gleason评分与临床分期进行对照比较。结果经病理证实413例中PCa 149例,前列腺增生171例,增生并炎症44例,增生并上皮内瘤(PIN)、非典型增生(AAH)共49例。前列腺癌与临床(Whitmore-Jewett法)A、B、C、D分期对照有一定的临床分期的超声声像图特征性表现,不同PCa临床分期的TRUS声像图特点:血清PSA、PPBCs及Gleason评分三者分别与PCa临床分期呈显著正相关。结论经直肠彩色多普勒超声能清晰显示前列腺内部结构,前列腺病变尤其是前列腺癌超声声像图有一定的特征性表现,结合PSA有助于提高前列腺病变诊断水平。Objective To observe and explore the characteristics of ultrasonography for transrectal color Doppler ultrasound in the diagnosis of hypertophy of the prostate disease and specific antigen（ PSA） and image fea-tures in clinical stages of prostate cancer（ PCa）systematically.Methods Patients clinically suspected of PCa under -went prostate exam by transrectal color doppler ultrasound, then by transrectal ultrasound guided prostate biopsy by 6 points adding suspected nodes method,comparing with the PSA, pathologic results, PPBCs, Gleason score, and clin-ical stages.Results In 413 patients confirmed by pathology（149 PCa, 171 BPH, 44 BPH with inflammation, 49 BPH with PIN and AAH）, prostate disease had some characteristic ultrasound images.Clinical stages A,B,C or D （ Whitmore-Jewett methods） of PCa had some different characteristics of ultrasound images.The results showed that PSA, PPBCs and Gleason grades were positively correlated with PCa stages respectively.Conclusion Transrectalnbsp;color Doppler ultrasound not only clearly reveals the internal structure of prostate ,but also has the characteristic ultra-sound imaging.Combination of image features with PSA is helpful for improving the diagnosis of prostate disease .

关 键 词：经直肠超声 前列腺病变 病理学 PSA 

分 类 号：R445[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]