早期胃管灌注硫酸镁对急性胆源性胰腺炎患者的影响  

Effect Analysis on the Patients with Acute Biliary Pancreatitis Treated By Early-phase Stomach Tube Infusion of Magnesium Sulfate

作　　者：高文杰 冯建中 

机构地区：[1]封丘县人民医院普外科,河南封丘453300

出　　处：《河南医学高等专科学校学报》2015年第2期132-134,共3页Journal of Henan Medical College

摘　　要：目的探讨早期胃管灌注硫酸镁对急性胆源性胰腺炎患者白细胞、淀粉酶及急诊手术率的影响。方法选取该院于2009年8月-2014年8月收治的133例急性胆原性胰腺炎患者为研究对象,随机分成A组(n=67)与B组(n=66)2组。B组采用常规非手术疗法进行治疗,A组在上述治疗基础上辅以早期胃管灌注硫酸镁疗法进行治疗。观察分析2组患者治疗后淀粉酶、体温等各项指标降低率、自主排便率及急诊手术率对比情况;记录其疼痛缓解情况。结果 1A组治疗后WBC、淀粉酶等指标降低率、急诊手术发生率及自主排便率均高于B组患者,组间对比差异明显(P<0.05);2治疗后,A组患者VAS评分为(2.3±1.1)分,明显低于B组患者的(5.2±1.8)分,组间对比具有统计学意义(P<0.05)。结论对早期急性胆源性胰腺炎患者采用胃管灌注硫酸镁疗法,可有效缓解其部分早期症状,减少治疗后24 h内急诊手术发生率,利于患者自主排便,能加速胆管结石排除,缓解括约肌痉挛情况,对改善患者临床症状、减轻病痛等具有积极意义。Objective To discuss the effects of leukocytes , amylase and emergency operation rate of＆amp;nbsp;patients with acute biliary pancreatitis treated by early-phase stomach tube infusion of magnesium sulfate . Method 133casesofpatientswithacutebiliarypancreatitistreatedinourhospitalfromAugust2009to August 2014 were selected as the study objects .They were randomly divided into group A with 67 cases and group B with 66 cases.Patients in group B were given regular non-operative treatment , while those in group A were given early-phase stomach tube infusion of magnesium sulfate treatment combined with the aforementioned treatment .The decrease rate , independent defecation rate and emergency operation rate of amylase , temperature and other indexes were observed and analyzed of the two groups .Meanwhile , the easement rate of pain was recorded .Results After treatment, firstly, WBC, the decrease rate of amyl-ase and other common indexes , emergency operation rate and independent defecation rate in group A were all higher than those in group B and the differences between groups have a statistical significance （ P〈0.05）.Secondly, the VAS score of group A was （2.3 ±1.1）, which was obviously lower than that of group B’s 5.2 ±1.8） and the differences between groups have statistical significance （P〈0.05）.Con-clusion Applying early-phase stomach tube infusion of magnesium sulfate to patients with acute biliary pancreatitis can effectively remit incipient symptoms to some extent , decrease the emergency operation rate within 24 hours after treatment , be beneficial to independent defecation of patients , accelerate the elimination of calculus of bile duct , ease sphincter spasm and better improve clinical symptoms of patients and relieve pain .

关 键 词：胃管灌注硫酸镁 急性胆源性胰腺炎 白细胞 淀粉酶 急诊手术率 

分 类 号：R587[医药卫生—内分泌]