N,N′-二(4-氨基苯基)磺酰乙二胺的合成  

Synthesis of 4,4′-dianimo-N,N′-diphenylsulfonyl Ethylenediamine

作　　者：谢慧军[1] 张淑芬[2] 

机构地区：[1]宁夏大学化学化工学院,宁夏银川750021 [2]大连理工大学精细化工国家重点实验室,辽宁大连116024

出　　处：《河北师范大学学报（自然科学版）》2015年第3期232-238,共7页Journal of Hebei Normal University：Natural Science

基　　金：国家科技支撑计划(2011BAE07B01)

摘　　要：以N,N-二甲基甲酰胺（DMF）为溶剂、三乙胺为缚酸剂,以对乙酰氨基苯磺酰氯、乙二胺为原料,经胺化、水解反应制备了活性染料中间体——N,N′-二（4-氨基苯基）磺酰乙二胺.用FTIR,MS,1 HNMR表征了该物质的结构,研究了其紫外吸收和荧光光谱性质,通过实验建立了关键步骤胺化反应的优化条件,n（对乙酰氨基苯磺酰氯）∶n（乙二胺）∶n（三乙胺）=2.1∶1.0∶2.4、投料温度0~10℃、胺化反应温度30℃、反应时间2h.结果表明,该物质的收率83.6%,纯度98.93%（HPLC）.Using N, N-dimethyl formamide as orannic solvents and triethylamine as acid-binding agent, p-acetamidobenzene sulfonyl chloride and ethylenediamine as the raw materials,a reactive dye intermediates 4,4＇-dianimo-N,N＇-diphenylsulfonyl ethylenediamine was synthesized through two-step reactions of amina- tion and hydrolysis. The structure of product was characterized by means of FTIR, MS and ~HNMR. The UV spectra and the fluorescent spectrum were studied. The optimization conditions of amination,and the key step of synthesis,were set up through experiments：the molar ratio of n（p-acetamidobenzene sulfonyl chloride） ： n（ethylenediamine） ： n（triethylamine） was 2.1 ： 1.0 ： 2.4,feeding temperature was 0-10 ℃ , amination temperature was 30 ℃, reaction time was 2 h. The yield of product can reach 83.6%~ with the pu- rity of 98.93 %（HPLC）.

关 键 词：N N′-二(4-氨基苯基)磺酰乙二胺 胺化条件 活性染料中间体 

分 类 号：O623.732[理学—有机化学] TQ613[理学—化学]