水生动物组蛋白衍生抗菌肽的结构特征和抗菌活性研究进展  

Structure Characteristics and Antibacterial Activities of Histone-derived Antibacterial Peptides in Aquatic Animal

作　　者：费威[1] 李慧[1] 马龙洋[1] 裴超[1] 孔祥会[1] 

机构地区：[1]河南师范大学水产学院,河南新乡453007

出　　处：《河南农业科学》2015年第4期9-13,共5页Journal of Henan Agricultural Sciences

基　　金：河南省科技厅科技创新杰出青年计划项目(124100510017);河南省水产重点学科项目(2012)

摘　　要：新型抗菌肽取代传统抗生素是未来水产养殖业的发展趋势,组蛋白衍生抗菌肽是水生动物体内的一类重要抗菌肽,在水生动物机体免疫和抗病过程中扮演重要角色,为当前的研究热点。分别对水生动物4种代表性的组蛋白衍生抗菌肽(OncorhyncinⅡ、Buforins、Abhisin和HLP-1)的结构特征和抗菌效应进行综述,旨在为组蛋白衍生抗菌肽的深入研究和推广应用提供参考。New antimicrobial peptides replacing traditional antibiotics is a development trend in aquacul-ture in the future. The histone-derived antimicrobial peptides as one of the current research focuses which plays an important role in natural immunity and disease prevention,and is an important class of antimicro-bial peptides in aquatic animals. In this paper,the structure features and antimicrobial effects of four anti-microbial peptides（Oncorhyncin Ⅱ,Buforins,Abhisin and HLP-1） were reviewed. The aim was to pro-vide some references for the further researches on antimicrobial peptides derived from histone and its ap-plication in aquaculture.

关 键 词：组蛋白衍生抗菌肽 结构特征 抗菌效应 水生动物 

分 类 号：S859[农业科学—临床兽医学] Q51[农业科学—兽医学]