颅内动脉瘤破裂危险因素分析  

Risk factors for intracranial aneurysm rupture

作　　者：邓志刚[1] 张秋生[1] 何毅[1] 伍健明[1] 

机构地区：[1]深圳市第二人民医院神经外科,广东深圳518000

出　　处：《西部医学》2015年第6期873-875,共3页Medical Journal of West China

基　　金：深圳市科技计划项目(201103112)

摘　　要：目的 探讨导致颅内动脉瘤破裂的危险因素.方法 回顾分析2001年3月～2012年3月在我院确诊为颅内动脉瘤的260例患者的病历资料,根据动脉瘤破裂与否将研究对象分为破裂组（n=200）和未破裂组（n=60）,对两组患者的临床资料及动脉瘤相关特征资料进行搜集,并进行单因素分析筛选,然后行logistic回归分析.结果 颅内动脉瘤破裂发生较高的危险因素有动脉瘤家族史（OR=14.335,95％CI=3.172～64.785）、吸烟史（OR=18.225,95％CI=4.42,8～75.034）、后交通动脉瘤（OR=4.264,95％CI=1.642～11.071）和中等动脉瘤（OR=5.640,95％CI=2.331～213.640）.结论 导致颅内动脉瘤破裂的危险因素包括动脉瘤家族史、中等动脉瘤、后交通动脉瘤和吸烟史.Objective To investigate the risk factor st leading to intracranial aneurysm rupture. Methods 260 pa- tients according to the rupture of the aneurysm ruptured or not subjects were divided into groups （n= 200） and unrup- tured groups （n= 60）. The clinical data and information relevant characteristics of the aneurysm were collected. Univari- ate analysis was performed on two groups of screening, and then carried out using logistic regression analysis. Results The occurrence of a higher risk factor family history of aneurysms （OR= 14. 335,95 % CI= 3. 172-64. 785）, smoking his- tory （OR=18. 225,95%CI=4.42,8-75. 034）, posterior communicating artery aneurysm （OR= 4. 264,95%CI= 1. 642- 11. 071）, moderate aneurysm （OR=5. 640,95%CI：2. 331,213. 640）. Conclusion Cause of intracranial aneurysm rup- ture risk factors include family history of aneurysms, moderate aneurysms, posterior communicating artery aneurysm and smoking history.

关 键 词：颅内动脉瘤 破裂 危险因素 

分 类 号：R379.41[医药卫生—病原生物学]