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作 者:石泉贵[1] 冯东方[1] 陈芳芳[1] 石华英[1] 童静[1] 肖静[1] 黄淮霖[1]
出 处:《国际检验医学杂志》2015年第10期1385-1386,共2页International Journal of Laboratory Medicine
摘 要:目的了解高原红细胞增多症(HAPC)患者凝血功能的损伤状况。方法选择高HAPC患者69例,检测空腹血浆标本活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)、纤维蛋白原(Fbg)水平。以生活在同海拔地的健康人群作为高原对照组进行比较分析。结果 HAPC患者Fbg、APTT、TT水平均高于高原对照组(P<0.05),PT水平比较差异无统计学意义(P>0.05);动态观察表明,综合治疗可促进HAPC患者凝血功能恢复正常。结论 HAPC患者出血与凝血两个过程十分复杂,既包含生理性的适应过程,同时也包含着从生理适应到病理改变的演变过程。Objective To investigate changes of coagulation function in patients with high altitude polycythemia (HAPC) .Meth‐ods Activated partial thromboplastin time (APTT) ,prothrombin time (PT) ,thrombin time (TT) and fibrinogen (Fbg) were de‐tected and compared between 69 patients with HAPC and 60 healthy subjects (controls) .Results Fbg ,APTT and TT levels in pa‐tients with HAPC were higher than controls (P〈0 .05) ,while the difference of PT was not significant (P〉0 .05) .Dynamic obser‐vation indicated that comprehensive therapy could these recover coagulation function .Conclusion Hemorrhage and coagulation process in patients with HAPC could be very complicated ,including physiological adaptation and the process of physiology evolving into pathology .
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