2012～2014年无偿献血者抗-HCV筛查结果分析  

Analysis of HCV screening results from2012 to 2014

作　　者：耿雪芹 姜斌 周军兵 黄宏亮 

机构地区：[1]盐城市中心血站,江苏盐城224005

出　　处：《国际检验医学杂志》2015年第10期1410-1411,共2页International Journal of Laboratory Medicine

摘　　要：目的了解盐城地区献血者丙型肝炎病毒(HCV)感染情况。方法采用酶联免疫吸附法(ELISA)检测献血者抗-HCV,用荧光定量聚合酶链反应检测HCV RNA。结果盐城地区献血者抗-HCV阳性率为0.07%(109/163 782);109例抗-HCV阳性者中,80例为单试剂阳性,29例为双试剂阳性;初次献血者抗-HCV阳性80例,重复献血者抗-HCV阳性29例;符合核酸检测要求的72例单试剂抗-HCV阳性者均为HCV RNA阴性。结论盐城地区献血者抗-HCV阳性率低于普通人群,近三年献血者抗-HCV阳性率没有变化,抗-HCV单试剂阳性者核酸检测均为阴性。Objective To study the infection status of hepatitis C virus （HCV） in blood donors .Methods anti‐HCV was detec‐ted by using enzyme linked immunosorbent assay （ELISA） .HCV RNA was detected by using fluorescence quantitative polymerase chain reaction .Results The positive rate of anti‐HCV in blood donors was 0 .07% （109/163 782） .Among 109 positive donors ,80 donors were anti‐HCV positive while only one reagent was used ,and 29 donors were anti‐HCV positive when two reagents were used .80 cases were anti‐HCV positive in first donors and 29 cases were anti‐HCV positive in repeated donors .Among the 80 donors who were anti‐HCV positive while only one reagent was used ,72 samples according with the demand of nucleic acid test were tested by the nucleic acid test ,of whom HCV RNA was negative .Conclusion The positive rate of anti‐HCV in Yancheng donors could be lower than general population .There might be no change of positive rate of anti‐HCV in blood donors during the three years .The positive individuals could be negative in nucleic acid test while only one reagent was used in ELISA test .

关 键 词：献血者 丙型肝炎病毒 抗-HCV 筛查 

分 类 号：R446.6[医药卫生—诊断学]