微波联合利福平治疗渗出型结核性腹膜炎的临床研究  

Clinical effects of treating exudative tuberculous peritonitis by microwave and rifampicin

作　　者：齐海亮[1] 徐伟乐[2] 宋鑫亮[1] 王鹏[1] 杜秀然[1] 李明珠[1] 齐科雷[1] 苏宏伟[1] 

机构地区：[1]河北省胸科医院胸二科,河北石家庄050041 [2]河北省胸科医院胸三科,河北石家庄050041

出　　处：《皖南医学院学报》2015年第3期236-239,共4页Journal of Wannan Medical College

基　　金：河北省医学科学研究重点课题(ZL20140131)

摘　　要：目的：观察微波联合利福平治疗渗出型结核性腹膜炎的临床效果。方法：选取我科2009年3月-2014年3月渗出型结核性腹膜炎患者75例,随机分为治疗组和对照组,两组均给予相同的抗结核方案,即3HRZE/6HR,并行腹腔置管,注射无菌的利福平针剂;治疗组加用微波局部照射治疗,每次照射15 min,每日2次,治疗4周;对照组无微波照射;比较两组的治疗效果。结果：治疗组腹水消失快,腹腔积液总量少,效果明显优于对照组,相关指标有统计学意义（P〈0.05）,而并发症的发生率、不良反应和复发率无统计学差异（P〉0.05）。结论：采用微波照射联合利福平局部注射治疗渗出型结核性腹膜炎操作方便、效果明显,值得临床推广应用。Objective： To observe the clinical effects of treating exudative tuberculous peritonitis by combined microwave with rifampicin. Methods： Seventy-five patients with exudative tuberculous peritonitis treated in our department between March 2009 and March 2014 were included and randomly allocated to treatment group and control group. Both groups underwent similar anti-TB regimen（ i. e.,3HRZE /6HR,placement of parallel intraperitoneal catheter,sterile injection of rifampicin）,and the treatment group were given additional local microwave irradiation for consecutive 4 weeks,twice a day,15 min for each exposure. The therapeutic effects were evaluated for the two groups after treatment. Results： Ascites disappeared quickly and the total amount of peritoneal effusion was lessened in the treatment group,which produced better therapeutic effect than the control group（ P〈0. 05）,yet the two groups remained similarly regarding the incidence of complications,adverse events and relapse（ P〉0. 05）. Conclusion Combined focal microwave irradiation with rifampicin may be effective in treatment of exudative tuberculous peritonitis and worthy of clinical recommendation.

关 键 词：微波 利福平 腹腔内注药 渗出型 结核性腹膜炎 

分 类 号：R526[医药卫生—内科学]