宫颈高级别CIN术后残留临床结局研究  

Clinical Outcome of Postoperative Residue of Cervical High Grade CIN

作　　者：李晴[1] 汪艳珠[1] 黄卓敏[1] 金平[1] 

机构地区：[1]南方医科大学附属深圳市妇幼保健院,广东深圳518048

出　　处：《肿瘤学杂志》2015年第5期415-418,共4页Journal of Chinese Oncology

摘　　要：[目的]总结宫颈高级别CIN术后残留、复发特点,探讨CIN病例术后临床复诊的重要性。[方法]宫颈高级别CIN行锥切手术治疗595例,术后病理诊断残留58例,术后第4个月开始定期随访,随访手段为HPV检测、阴道镜检查、细胞学检查,必要时进行活检及ECC。[结果 ]595例手术后病灶残留58例,残留阳性率9.75%,其中CIN2残留阳性率1.46%,实际残留率0,HPV持续阳性率0;CIN3残留阳性率14.10%,实际残留率2.05%,HPV持续阳性率1.03%。[结论]高级别CIN术后病理诊断边缘或/和基底有病灶残留,需要在随访中进一步明确,对实际残留病例应把握处理时机及恰当的处理方法。[Purpose] To summarize the characteristics of postoperative residue and relapse of cervical high grade CIN and to investigate the importance of clinical follow-up of CIN postopera- tive patients. [Methods] Five hundred and ninety-five high grade CIN patients underwent conization. Among them, 58 patients were diagnosed as residual cases and were regularly followed up. Follow-up methods included HPV DNA genotyping,eolposcope,cytologic examination,and performing biopsy and ECC when necessary. [Results] The overall residual positive rate of 595 postoperative patients was 9.75%（58 eases）. The residual positive rate of CIN2,the actual residual rate and the continual positive rate of HPV xere 1.46%,0 and 0,respectively. The residual posi- tive rate of CIN3,the actual residual rate and the continual positive rate of HPV were 14.10%, 2.05% and 1.03% ,respectively. [Conclusion] Postoperative follow-up should perform on high grade CIN patients if residual lesion is diagnosed in margin and/or base tissue after opertation. Postoperative actual residual patients should be dealed with at an appropriate time and in a ProPer method.

关 键 词：宫颈上皮内瘤变 残留 复发 环状电极切除术(LEEP) 冷刀锥切术(CKC) 

分 类 号：R711.74[医药卫生—妇产科学]