微波协同离子液体催化合成马来酸二丁酯  

Microwave-assisted catalytic synthesis of dibutyl maleate by ionic liquid catalyst

作　　者：黄飞[1] 屈飞强 任晓琼[1] 魏先文[2] 

机构地区：[1]黄山学院化学化工学院,安徽黄山245041 [2]安徽工业大学化学与化工学院,安徽马鞍山243002

出　　处：《化学研究与应用》2015年第5期566-572,共7页Chemical Research and Application

基　　金：国家自然科学基金项目(21071005;21271006)资助;国家级大学生创新创业训练计划项目(201410375003)资助;安徽省大学生创新创业训练项目(AH201310375027)资助

摘　　要：以马来酸酐和正丁醇为原料,用微波协同离子液体[HSO3-pmim]+[HSO4]-催化合成了马来酸二丁酯。通过单因素实验和正交试验考察催化剂种类、催化剂用量、马来酸酐与正丁醇物质的量比、微波功率、微波时间对马来酸二丁酯产率的影响。实验结果表明,马来酸二丁酯最佳合成条件为:马来酸酐与正丁醇物质的量比1∶4,以离子液体[HSO3-pmim]+[HSO4]-为催化剂,其用量为2.0g,微波功率为600W,微波时间为15min,马来酸二丁酯产率可达到99.36%。在微波辐射下,催化剂离子液体[HSO3-pmim]+[HSO4]-重复使用7次后活性没有明显降低,马来酸二丁酯产率仍高于96%,表明该催化剂具有较好的反应活性和稳定性。与常规加热方式相比,微波加热提高了反应效率,缩短了反应时间。Dibutyl maleate was synthesized from maleic anhydride and n-butanol using ionic liquid[ HSO3-pmim]＋[ HSO4 ]-as cat-alyst under microwave irradiation. The molar ratio of maleic anhydride and n-butanol,the type of catalysts and dosage,microwave power and irradiated time were explored by single factor experiment and orthogonal experiment. The results showed that optimal con-ditions were the molar ratio of maleic anhydride and n-butanol was 1∶4,dosage of ionic liquid[HSO3-pmim]＋[HSO4]-catalyst was 2. 0g,microwave power was 600W,and microwave irradiated time was 15min. The yield of dibutyl maleate was up to 99. 36%under the optimized condition. The ionic liquid[ HSO3-pmim]＋[ HSO4 ]-exhibited excellent stability and catalytic activity under the reac-tion conditions. Moreover, it could be reused seven times without considerable loss of activity with at least 96% conver-sion. Compared with conventional heating,microwave irradiation enhanced catalytic efficiency,as well as reduced reaction time.

关 键 词：马来酸二丁酯 离子液体[HSO3-pmim]^+[HSO4]^- 微波协同 催化合成 

分 类 号：O622.5[理学—有机化学]