赴南苏丹维和人员甲状腺及皮质醇激素变化的研究  

Study of thyroid and corticosteroid hormone in peacekeepers for South Sudan

作　　者：李广文[1] 孙中安[1] 吕春雷[2] 孔莉[1] 宋伟[1] 

机构地区：[1] 解放军第八十八医院内分泌科,山东省泰安271000 [2] 解放军第八十八医院医务处,山东省泰安271000

出　　处：《中国基层医药》2015年第10期1481-1483,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的：观察维和队员在南苏丹恶劣的环境所导致的应激状态下甲状腺激素和皮质醇激素的水平，探讨机体遭受应激后激素的变化及其相关原因。方法25名维和队员分别于出国前、出国后1个月、出国后4个月、出国后7个月各采血一次。采用磁分离免疫测定法，测定甲状腺和皮质醇激素水平变化，并分别与出国前比较。结果出国后1个月 T3（1．780±0．345）ng／mL、T4（88．609±14．486）ng／mL、FT3（3．758±4.287）pg／mL、FT4（15．152±6．422）pg／mL，均较出国的（1．458±0．206）ng／mL、（2．060±0．642）ng／mL、（11.672±3．627）pg／mL、（96．958±12．286）pg／mL 明显升高（t ＝3．670、2．410、2．019、2．798，均 P ＜0．0）。出国后4个月 TSH（1．320±0．518）μIU ／mL，较出国前的（1．872±0．821）μIU ／mL 明显降低（t ＝3．175，P ＜0.05）。结论机体在环境改变等应激因素作用下，甲状腺激素和皮质醇激素的水平均有明显的变化，建议尽早作出对策，进行适当干预。同时对维和队员在出国前全面进行一次激素检测和心理疏导，对顺利完成维和任务意义重大。Objective To observe level of thyroid and corticosteroid hormone of peacekeepers in South Sudan the harsh environment under stress and explore the changes of hormone and its related causes the body to suffer stress.Methods 25 peacekeepers were drawn blood before going abroad,after going abroad 1 months,4 months and 7 months,respectively.Methods of immune by magnetic separation were adopted and determined the changes of thyroid hormone and cortisol levels.They were compared with before going abroad.Results After going abroad 1 months T3 （1.780 ±0.345）ng/mL,T4 （88.609 ±14.486）ng/mL,FT3 （3.758 ±4.287）pg/mL,FT4 （15.152 ±6.422）pg/mL than before going abroad （1.458 ±0.206）ng/mL,（2.060 ±0.642）ng/mL,（11.672 ±3.627）pg/mL,（96.958 ± 12.286）pg/mL were significantly increased （t =3.670,2.410,2.019,2.798,all P 〈0.0 ）.TSH （1.320 ± 0.518）μIU /mL after going abroad 4 months was lower than before going abroad（1.872 ±0.821）μIU /mL decreased significantly（t =3.175,P 〈0.05）.Conclusion In the role of the environment change of stress factors,changes of thyroid hormone and cortisol levels of body were obvious.We suggest to make countermeasure as soon as possible and appropriate intervention.At the same time the peacekeepers are detected comprehensive hormone detection and psy-chological counseling before going abroad,it is significant for the successful completion of peace -keeping task.

关 键 词：南苏丹 维和人员 甲状腺激素 皮质醇 

分 类 号：R446.6[医药卫生—诊断学]