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出 处:《中国伤残医学》2015年第11期25-26,共2页Chinese Journal of Trauma and Disability Medicine
基 金:龙岩市医疗领域重点攻关项目(2013LY57)
摘 要:目的:通过研究终末期肾病血液透析患者出凝血功能及肾功能变化,分析探讨血液透析治疗的临床意义。方法:取经临床及实验室诊断明确的终末期肾病患者68例,检测血液透析治疗前后患者外周血PLT、MPV、PDW、PT、APTT、TT、FIB、肾功能等。结果:血液透析治疗后患者外周血PLT、MPV、PDW、PT、TT、FIB无显著性差异(P〉0.05);APTT、肾功能有显著性差异(P〉0.05),比较有统计学意义(P〈0.05)。结论:血液透析治疗终末期肾病可明显改善肾功能,但无法明显改善高凝状态。Objective: To investigate hemorrhage, coagulation and Renal function with end stage renal disease (ESRD) undergoing hemodialysis (HD). Methods: 68 patients were studied and their bloods were sampled at the day on HD for the de - termination of plate- let (PIT), mean platelet volume (MPV) , platelet distribution width (PDW), prothrombin time (PT), active part thrombin time (AFYY), thrombin time (TY), fibrinogen(FIB), Renal function. Results: The levels of PiT, PT, TY, FIB in ESRD maintenance HI) patients were no significant difference ( P 〉 0.05 ) ; but the levels of APTT, Renal function were a statistically difference ( P 〈 0.05 ) with ESRD maintenance HD. Conclusion: The effect in ESRD maintenance HD patients could not improve hypereoagulation effectively, but apparently improve the patientg Renal function.
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