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作 者:陈莹[1] 卢眺眺 朱翔贞[2] 陈春凤[2] 高静芳[2]
机构地区:[1]浙江中医药大学,杭州310053 [2]浙江中医药大学附属第一医院
出 处:《浙江中医药大学学报》2015年第4期278-281,共4页Journal of Zhejiang Chinese Medical University
基 金:浙江省自然科学基金资助项目(Y12H090040)~~
摘 要:[目的]探讨抑郁症患者在愤怒或恐惧情绪下风险决策能力及其行为倾向。[方法]通过情景诱发愤怒情绪的抑郁症患者组和正常对照组各20例,诱发恐惧情绪的抑郁症患者组和正常对照组各20例,所有被试者在情绪诱发后均执行风险决策实验,观察抑郁症患者和正常人在不同情绪下执行风险决策的差异。[结果](1)在愤怒情绪下,抑郁症患者组惩罚后的安全选择的频率均值比正常对照组高,差异有统计学意义(P<0.05),惩罚后的风险选择的频率均值比正常对照组低,且差异有统计学意义(P<0.05);抑郁症患者组奖赏后安全选择的频率均值比正常对照组高,差异有统计学意义(P<0.01),奖赏后风险选择的频率均值比正常对照组低,差异有统计学意义(P<0.01)。(2)在恐惧情绪下,抑郁症患者组奖赏后安全选择的频率均值比正常对照组高,差异有统计学意义(P<0.05),奖赏后风险选择的频率均值比正常对照组低,差异有统计学意义(P<0.05)。[结论]抑郁症患者在愤怒情绪下,面对惩罚刺激和奖赏刺激倾向于低风险选择;在恐惧情绪下,抑郁症患者面对奖赏刺激选择较保守。[Objective]To study the difference of risk decision-makings between patients with unipolar depressive disorder and healthy controls when they axe evoked angry mood or fear mood.[Method]Twenty cases of depression patient group and normal control group were induced by angry mood, while other twenty cases of the two groups were evoked by fear mood. Participants did risk decision making. Differences were observed in patients with depression execution risk decisions under different moods. [Result]( I ) Comparison of angry depression patients with normal control group of frequency of risk decision: the average frequency of depression patients safe choice after punishment was higher them the normal control group, the difference was statistically significant(P〈0.05), while the average frequency of the risk choice of the depression group after punishment was lower than the normal control group, and the difference was statistically significant(P〈0.05); The frequency of safe choice of patients with depression after reward was higher than the normal control group, and the mean difference was statistically significant(P〈0.01). The frequency of risk selection after the reward was lower than the mean of the normal control group, and the difference was statistically significant(P〈0.01). ( Ⅱ ) In the mood of fear, comparing depression patients with normal control group on risk decision to select the comparison frequency: patients with depression after reward safe selected frequency was higher than the normal control group, the mean difference was statistically significant(P〈0.05), the frequency of risk selection after the reward was lower than the mean of the normal control group, the difference was statistically significant(P〈0.05). [Conclusion]In the mood of anger, depression patients are more sensitive to punishment and relatively slow to reward stimuli while in feelings of fear, depression patients are relatively slow to reward stimuli.
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