Phytochemistry,Metabolism, and Metabolomics of Ginseng  

作　　者：Xiao-peng Chen Yan-ping Lin Yao-zhong Hu Chang-xiao Liu Ke Lan Wei Jia 

机构地区：[1]Department of Molecular Biosciences, School of Veterinary Medicine, University of California [2]Tasly Academy,Tasly Holding Group [3]Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel [4]School of Chemical Engineering and Technology, Tianjin University [5]State Key Laboratory of Drug Delivery Technology and Pharmacokinetics [6]Cancer Epidemiology, University of Hawaii Cancer Center

出　　处：《Chinese Herbal Medicines》2015年第2期98-108,共11页中草药（英文版）

摘　　要：Ginseng, as a medicinal plant, has been used for thousands of years in China, Korea, and Japan, and the study on ginseng is a hotspot in the research field as evidenced by about 7000 scientific papers in PUBMED. In recent decades, many ginseng studies focused on the metabolism and metabolomics of ginseng or its active ingredients using modern bioanalytical technologies. To date, more than 200 ginsenosides and non-saponin constituents have been isolated and identified. In the past decades, rapid development of analytical technologies has facilitated the advancement of ginseng research in many ways. In this review, we focus on the advances of ginseng research in chemistry, pharmacology, and metabolomics. We also provide the comments on the significance as well as challenges of metabolomics-based ginseng studies.Ginseng, as a medicinal plant, has been used for thousands of years in China, Korea, and Japan, and the study on ginseng is a hotspot in the research field as evidenced by about 7000 scientific papers in PUBMED. In recent decades, many ginseng studies focused on the metabolism and metabolomics of ginseng or its active ingredients using modern bioanalytical technologies. To date, more than 200 ginsenosides and non-saponin constituents have been isolated and identified. In the past decades, rapid development of analytical technologies has facilitated the advancement of ginseng research in many ways. In this review, we focus on the advances of ginseng research in chemistry, pharmacology, and metabolomics. We also provide the comments on the significance as well as challenges of metabolomics-based ginseng studies.

关 键 词：ginseng ginsenoside herbal medicines metabolomics metabonomics pharmacology traditional Chinese medicines 

分 类 号：R284[医药卫生—中药学]