钬激光与等离子技术对治疗良性前列腺增生的疗效比较  

A comparative study on holmium laser enucleation of prostate and transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia

作　　者：庞程[1] 邱敏捷[2] 杨志坚[1] 刘肇华[1] 陈敏坚[1] 徐乐[2] 

机构地区：[1]广东省肇庆市第一人民医院泌尿外科,广东肇庆526040 [2]南方医科大学附属何贤医院泌尿外科,广东广州511400

出　　处：《中国内镜杂志》2015年第5期521-524,共4页China Journal of Endoscopy

基　　金：肇庆市科技局(2011)91号(No:2011E222)

摘　　要：目的比较经尿道前列腺等离子电切术与经尿道钬激光前列腺剜除术的疗效。方法将254例良性前列腺增生症患者按手术方式的不同,分为钬激光组(Ho LEP组,128例)和等离子电切组(PKRP组,126例)。比较两种术式的手术时间、手术出血量、膀胱冲洗时间、住院时间、并发症及近期疗效等指标。结果所有患者均顺利完成手术,无1例中转开放手术。Ho LEP组的手术时间明显长于PKRP组,但在术中出血量、术后持续膀胱冲洗时间、术后并发症发生率及住院时间方面,显著优于PKRP组。两组患者术后国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(Qmax)和残余尿量(PVR)均较术前明显改善,但两组上述指标间比较差异无显著性。结论 Ho LEP是一种疗效显著、安全性高的治疗前列腺增生的手术方式,有望挑战PKRP成为治疗BPH的新的金标准。[Objective] To compare the effects of holmium laser enucleation of prostate （HoLEP） and transurethral plasmakinetic resection of prostate （PKRP） for treatment of patients with benign prostatic hyperplasia （BPH）. [Methods] A total of 254 patients with BPH were divided into HoLEP group （n =128） and PKRP group （n = 126）. The operative time, blood loss in operation,irrigation time,hospital stay time,complications and clinic effectiveness in two groups were analyzed retrospectively. [ Results ] The operation was completed in all the cases, none of them conversed to open surgery. The IPSS, QOL, Qmax, PVR were greatly improved in both groups after operations （P 〈0.01）, and the differences between these two groups were not significant （P 〉0.05）. The incidence of hemorrhage, the mean bladder irrigating time, hospital stay time in HoLEP group were less or shorter than those in PKRP group （P 〈0.01）. The incidences of complications after operation in HoLEP group were lower than PKRP group. [ Conclusion ] HoLEP is an effective and safe procedure, which should be proposed as a potential surgical therapy challeng- ing transurethral plasmakinetic resection in the treatment of patients with BPH.

关 键 词：前列腺增生症 钬激光 前列腺等离子电切术 

分 类 号：R697.3[医药卫生—泌尿科学]