急性深静脉血栓患者早期下床活动与卧床休息的系统评价  

Systematic evaluation of early ambulation and bed rest for patients with acute deep venous thrombosis

作　　者：翁艳秋 刘莹[1] 刘颖[1] 张玲娟[1] 

机构地区：[1]上海长海医院,上海200433

出　　处：《护士进修杂志》2015年第11期999-1003,共5页Journal of Nurses Training

基　　金：长海医院护理学科建设系列研究项目(编号:CH125531000)

摘　　要：目的评价与卧床休息相比,早期下床活动对急性深静脉血栓患者继发肺栓塞率的有效性。方法运用计算机检索Cochrane、JBI、Medline、EMbase、CINAHL、Web of Knowledge、CBM、万方和CNKI数据库,查找关于对比早期下床活动和卧床休息处理急性深静脉血栓患者继发肺栓塞问题的相关研究文献。检索时间均从建库至2015年1月1日。由2位评价员按纳入与排除标准独立筛选文献、提取资料并评价质量后,采用RevMan 5.3软件进行Meta分析。结果共纳入9项研究,共847例患者。Meta分析结果显示:与卧床休息相比,早期下床活动对急性深静脉血栓患者继发肺栓塞率[RR=0.42,95%CI(0.16,1.09),P=0.08]差异无统计学意义。结论现有证据表明:早期下床活动不会增加深静脉血栓患者继发肺栓塞率。鉴于纳入研究数量有限,上述结论尚需开展更多研究予以验证。Objective Systematic review the secondary pulmonary embolism rate ofearly mobilization for patients with acute deep venous thrombosis compared with bed rest .Method Search the databases of Cochrane ,JBI ,Med‐line ,EMbase ,CINAHL ,Web of Knowledge ,CBM ,Wanfang and CNKI ,for the literatures about the secondary pulmonary embolism rate for patients with acute deep venous thrombosis under early mobilization .Retrieval time from the foundation of the database to January 1 ,2005 .Two valuators screen the literature ,extract data ,and evalu‐ate the quality of the articles separately .RevMan 5 .3 software was used for Mate analysis .Result There were 9 studies with 847 patients included in this research .Meta analysis showed that there was no statistically significant difference in the rate of secondary pulmonary embolism between two groups[RR= 0 .42 ,95% CI（0 .16 ,1 .09） , P=0 .08] Conclusion Existing evidence suggests that early mobilization will not increase the rate of secondary pul‐monary embolism for patients with deep venous thrombosis .Given the limited number of incorporating researches , the conclusion still needs more research to verify .

关 键 词：早期下床活动 继发肺栓塞率 急性深静脉血栓患者 系统评价 M eta分析 

分 类 号：R471[医药卫生—护理学] R472[医药卫生—临床医学]