不同年龄组吸烟患者经皮冠状动脉介入治疗后复吸危险因素差异分析  

Discrepancy of Independent Risk Factors of Smoking Relapse in Different Age Patients after Percutaneous Coronary Intervention

作　　者：张一径[1] 韩硕[2] 金元哲[2] 

机构地区：[1]中国医科大学附属第四医院重症医学科,沈阳110032 [2]中国医科大学附属第四医院心内科,沈阳110032

出　　处：《中国医科大学学报》2015年第6期538-542,共5页Journal of China Medical University

摘　　要：目的探讨不同年龄组的当前吸烟患者在接受经皮冠状动脉介入治疗(PCI)后复吸的独立危险因素。方法对接受PCI治疗的197例当前吸烟患者,进行病史采集及电话随访,比较出院后复吸的危险因素在不同年龄组患者中的差异。结果所有被征集的患者中,PCI术后复吸者为112例,其中非老年组87例,老年组25例。相关性分析提示非老年组患者中植入多枚支架(P=0.025)、重度尼古丁依赖(P=0.001)、每日被动吸烟时间长(P=0.000)可能与复吸相关,其中植入多枚支架与复吸负相关。而老年组中复吸与既往高血压病史(P=0.034)相关。按不同年龄组分别进行Logistic回归分析,非老年组患者复吸的独立危险因素包括重度尼古丁依赖(OR:3.914,P=0.003)和每日被动吸烟时间(OR:1.352,P=0.000);而老年组患者为:男性(OR:17.325,P=0.027)、既往高血压病史(OR:13.185,P=0.005)、每日被动吸烟时间(OR:1.273,P=0.045)。结论在接受PCI治疗的吸烟患者中,老年组与非老年组患者复吸的危险因素不同;在非老年组患者中,重度尼古丁依赖及每日被动吸烟时间是复吸的独立危险因素;在老年组患者中,男性、既往高血压病史、每日被动吸烟时间是复吸的独立危险因素。Objective To study the independent risk factors of relapse of smoking among current smokers of different ages who underwent percutaneous coronary intervention（PCI）. Methods Totally 197 current smokers who received PCI from January 2007 to December 2009 in the Fourth Affiliated Hospital of China Medical University were enrolled. Information about relapse of smoking was collected through the medical records and the telephone follow-up. Discrepancy of risk factors of smoking resumption was compared in different age groups. Results Totally 112 patients resumed smoking after PCI. There were 87 patients in the non-elderly group and 25 in the elderly group. According to the correlation analysis,more than one stents（P = 0.025）,severe nicotine dependence（P = 0.001）and long time for daily passive smoking（P = 0.000）were related with relapse in the non-elderly group,and there was a negative correlation between more than one stents and relapse. But in the elderly group,relapse was associated with history of hypertension（P = 0.034）. According to the logistic regression analysis in different age groups,independent predictors of smoking relapse in the non-elderly group were severe nicotine dependence（OR：3.914,P = 0.003）and long time for daily passive smoking（OR：1.352,P =0.000）. And in the elderly group,independent risk factors of smoking relapse were male（OR：17.325,P = 0.027）,history of hypertension（OR：13.185,P = 0.005）,long time for daily passive smoking（OR：1.273,P = 0.045）Conclusion Independent risk factors of smoking relapse were different in the elderly group and the non-elderly group. In the non-elderly group,these factors were severe nicotine dependence and long time for daily passive smoking. And in elderly group,these factors were male,history of hypertension,long time for daily passive smoking.

关 键 词：年龄 经皮冠状动脉介入治疗 吸烟 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]