Chemerin 与阻塞性睡眠呼吸暂停低通气综合征  

Chemerin and obstructive sleep apnea hypopnea syndrome

作　　者：高裕盛 姜秀峰[1] 

机构地区：[1]南京医科大学附属无锡市人民医院呼吸内科,214023

出　　处：《国际呼吸杂志》2015年第10期779-783,共5页International Journal of Respiration

基　　金：无锡市卫生局指令性面上项目（ML201319）

摘　　要：OSAHS 发病率逐年升高,已成为危害人类健康的主要疾病之一,OSAHS 的发病机制目前尚未完全阐明。chemerin 作为一种新的脂肪因子,可通过自分泌、旁分泌、内分泌等形式作用于机体脂肪细胞,促进脂肪细胞的分化、脂解,影响糖脂代谢；并可参与机体的血压调节、免疫应答及炎症反应等,与 OSAHS 的发生有密切的联系。本文就脂肪因子 chemerin 与 OSAHS 的相关性进行简要综述。The incidence of OSAHS increased year by year,and OSAHS has become one of the major diseases that endangers human health.The pathogenesis of OSAHS is not yet entirely clear.As a novel adipokine,chemerin effects fat cells through autocrine,paracrine and endocrine in the body.It can promote adipocyte differentiation and lipolysis,affect glucose lipid metabolism and blood pressure regulation,and be involved in the body′s immune response and inflammation.Chemerin is closely linked with OSAHS.We review the recent researches concerned about chemerin and OSAHS in this article.

关 键 词：睡眠呼吸暂停低通气综合征 脂肪代谢 

分 类 号：R766[医药卫生—耳鼻咽喉科]