660例老年性痴呆患者中医症状整理与分析  

Correlation Analysis on AD Symptoms of Traditional Chinese Medicine with the Theory of the Kidney Storing Essence

作　　者：崔远武[1] 张玉莲[1] 李强[2] 张连城[1] 顾耘[3] 汪振宇 李柱 吴迪[6] 崔俊波 

机构地区：[1]天津中医药大学第二附属医院,天津300150 [2]天津中医药大学,天津300150 [3]上海中医药大学附属龙华医院,上海20000 [4]营口市中医院,辽宁营口115000 [5]开封市中医院,河南开封475000 [6]天津市环湖医院,天津300150 [7]天津市武清中医院,天津300150

出　　处：《中华中医药学刊》2015年第6期1356-1359,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金青年项目(81102577);国家重点基础研究发展计划(973计划)项目(2010CB530405)

摘　　要：目的：通过对660例老年性痴呆患者的中医临床症状资料整理和分析,总结本病临床高频症状和症状群特点,在此基础上探讨其发生发展与中医＂肾藏精＂理论内在相关性。方法：采用横断面调查,对年龄为60~85岁（含60岁与85岁）以记忆力减退为主诉的社区居民和门诊就诊患者共计13297人进行了初步筛查,根据国际统一的痴呆和老年性痴呆诊断标准（DSM-IV标准）,对符合诊断标准的660例AD患者进行中医证候问卷调查,在此基础上采用描述性统计方法分别从认知功能,行为与精神障碍,生活能力,常见身体特征四个方面对AD患者的临床症状进行统计和分析。结果：认知功能方面常见症状有善忘（近事遗忘、远事遗忘、瞬间遗忘转盼遗忘）、失算、反应迟钝、失用、寡言少语、失认等;在行为与精神障碍方面常见症状有烦躁易怒、表情淡漠、两眼无神、顽固迂执、多疑善虑、性情孤僻等;在生活能力相关症状有步履迟缓、纳呆、倦怠思卧、夜寐不安、耳聋、不闻香臭;本病的常见身体特征包括齿脱、发白、齿摇、唇淡白、耳轮枯槁、肌肤不荣等。结论：AD临床症状产生、发展和转归与肾精密切相关,中医＂肾藏精＂理论对AD病情评估和治疗具有重要的理论指导意义。Objective ： Based on 660 cases of patients with AD of traditional Chinese medicine clinical symptom infor- mation collection and analysis it summarized the characteristics of symptoms, and on the basis to analyze and discuss the inner correlation of symptoms with the traditional Chinese medicine theory of the kidney storing essence. Methods ： By using cross - sectional survey, the age of 60--85 （ including 60 and 85 years old） with memory loss patients complained of com- munity residents and clinics,a total of 13297 people were carried on the preliminary screening according to the interna- tional uniform diagnostic criteria （DSM- iv criteria）. In the diagnosis of dementia and AD, conforming to the diagnostic standard 660 patients with AD questionnaire, syndromes were conducted on the basis of the descriptive statistical methods, respectively from the cognitive function, behavior and mental disorders, life ability, the common physical features four as- pects of statistics and analysis on the clinical symptoms in patients with AD. Results ： The cognitive function in common symptoms were amnesia （ recent amnesia, anterograde amnesia, Instantly amnesia）, miscalculation, unresponsive, disuse, quiet, agnosia, etc. In terms of behavior and mental disorders common symptom were irritability,indifference, eyes glaze o- ver, stubborn, suspicious, character withdrawn, etc. Symptoms in life ability were walk slowly, anorexia, night insomnia, tired lying,deafness,lost sense of smell. Common physical characteristics were tooth to take off, white hair, tine shakes, pale lips, helix bent, skin withered, etc. Conclusion ： The clinical symptoms of AD production, development and outcome are closely related to the kidney essence, the TCM theory of ＂the kidney storing essence has important theoretical guiding sig- nificance to AD assessment and treatment.

关 键 词：老年性痴呆 流行病学调查 中医症状 “肾藏精”理论 

分 类 号：R259[医药卫生—中西医结合]