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作 者:叶一萍[1] 丁晓媚[1] 王法明[1] 郑宋明[1]
出 处:《中华中医药学刊》2015年第6期1398-1400,共3页Chinese Archives of Traditional Chinese Medicine
基 金:浙江省中医药科学研究基金计划项目(2012ZA134)
摘 要:目的:观察马齿苋在临床中对糖尿病合并高脂血症的疗效。方法:随机抽取门诊糖尿病合并高脂血症患者,所有病例经口服降糖药或注射胰岛素治疗,使空腹血糖控制在10 mmol/L左右。随机分为对照组、低剂量治疗组和高剂量治疗组。低剂量治疗组给予马齿苋(15 g,3次/d);高剂量治疗组患者给予马齿苋(30 g,3次/d);对照组给予口服辛伐他汀20 mg/d,晚间顿服,疗程为4周。结果:1低剂量治疗组、对照组本组治疗前后相比较,空腹血糖、糖化血红蛋白均无统计学差异P>0.05;高剂量治疗组治疗前后相比较空腹血糖、糖化血红蛋白有统计学差异(P<0.05)。2低剂量组治疗前后相比总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白均无统计学差异P>0.05;高剂量治疗组、对照组本组治疗前后相比较有明显统计学差异(P<0.05);3与对照组治疗后相比较,高剂量治疗组总胆固醇、甘油三酯、高密度脂蛋白均未见明显统计学意义(P>0.05);与对照组治疗后相比较,高剂量治疗组低密度脂蛋白有明显统计学意义(P<0.05)。结论:马齿苋(30 g,3次/d)能同时治疗糖尿病合并高脂血症患者的血糖和血脂的作用。Objective: In our experiment we will investigat the effect of purslane on the hyperlipemia complicated with diabetic. Methods: We randomly divided the patients of the hyperlipemia complicated with diabetic into control group,experimental group with low- dose and experimental group with high- dose. The experimental group with high- dose was treatedwith purslane( 3 0 g,3 times a day). The experimental group with low- dose was treated with purslane( 1 5 g,3times a day),the control group were given Simvastatin tablets( 20 mg,once a day). Treatment for 4 weeks. Results: 1In the control group and the experimental group with low- dose,fasting blood glucose,Glycated hemoglobin was the same compared with that before the treatment( P〉0. 05) that before; Tn in the experimental group with high- dose,fasting blood glucose,Glycated hemoglobin are different compared with that before the treatment( P〈0. 05). 2In the experimental group with low- dose,TC. TG. IDL- C,HDL- C were the same compared with that before the treatment( P〈0. 05); In the control group and the experimental group with high- dose TC,TG,IDL- C,HDL- C were the different compared with that before the treatment( P〈0. 05). 3Compare with the control,the TC、TG and HDL- C in the experimental group with high- dose were the same after treatment for 4 weeks( P〉0. 05). But the result of IDL- C was different( P〈0. 05).Conclusion: Purslane( 30 g,3 times a day) treatment can significantly reduce the blood glucose and blood sugar.
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