小柴胡颗粒联合盐酸氨溴索治疗慢性支气管炎临床疗效  

Xiaochaihu Particle and Ambroxol Hydrochloride Clinical Efficacy in Treating Chronic Bronchitis

作　　者：刘姗姗[1] 徐丘卡[1] 陈锐[1] 胡炜科[2] 

机构地区：[1]宁波市妇女儿童医院内科,浙江宁波315000 [2]宁波市第一医院内科,浙江宁波315000

出　　处：《中华中医药学刊》2015年第6期1495-1497,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨小柴胡颗粒联合盐酸氨溴索治疗慢性支气管炎临床疗效,为临床诊断治疗提供一定的科学依据。方法:本组94例慢性支气管炎患者根据随机数字表法随机分为对照组和观察组,各47例;对照组给予盐酸氨溴索治疗,观察组在对照组基础上给予小柴胡颗粒治疗。两组均以7 d为1个疗程,2个疗程后评价其疗效。结果:观察组治疗后总有效率(95.75%)显著高于对照组(76.60%),且有统计学差异(P<0.05);观察组治疗后FEV1、FEV1%均显著高于治疗前及对照组治疗后,且均具有统计学差异(P<0.05);观察组治疗后咳痰、咳嗽,喘息及呼吸困难消失时间均显著低于对照组,且有统计学差异(P<0.05);两组患者治疗过程中均未发生明显的不良反应。结论:小柴胡颗粒联合盐酸氨溴索治疗慢性支气管炎临床疗效显著,且无明显不良反应,临床应用安全可靠,具有重要研究价值。Objective： To investigate Xiaochaihu particles and ambroxol hydrochloride clinical efficacy in treating chronic bronchitis,providing a scientific basis for clinical diagnosis and treatment. Methods： 94 cases of chronic bronchitis in this group according to the random number table were randomly divided in the control group（ n = 4 7） and the observation group（ n = 47）; control group was given ambroxol and treatment group received Xiaochaihu particles on the basis of treatment in the cortrol group. 7d for a course of treatment,after two courses to evaluate its efficacy. Results： The total effective rate（ 95. 75%） was significantly higher（ 76. 60%） after treatment,and there was statistically significant difference（ P〈0. 05）; observation group after treatment FEV1,FEV1% were significantly higher than those before the treatment and in control after the treatment group,and both had significant differences（ P〈0. 05）; observation group after treatment sputum,coughing,wheezing and shortness of breath had significantly less disappearance time than that of the control group,and there was significant difference（ P〈0. 05）; significant adverse reactions in two groups patients during treatment did not occur. Conclusion： Combined Xiaochaihu particles and ambroxol hydrochloride treatment of chronic bronchitis has significant clinical effect and no significant adverse reactions. Its clinical application is safe and reliable with important research value.

关 键 词：小柴胡颗粒 盐酸氨溴索 慢性支气管炎 

分 类 号：R562.21[医药卫生—呼吸系统]