抑郁症患者的情绪对认知功能的影响  

Effects of emotion on cognitive function in depression

作　　者：田菊[1] 王久菊 权文香[1] 王鹏飞 刘津[1] 董问天[1] 

机构地区：[1]北京大学第六医院,北京大学精神卫生研究所,卫生部精神卫生学重点实验室,北京100191

出　　处：《中华行为医学与脑科学杂志》2015年第4期329-331,共3页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：基金项目：北京市科技计划重点项目（D121100005012004）

摘　　要：目的 探讨抑郁症患者情绪对认知功能的影响.方法 对2012年6月至2013年10月就诊的门诊及住院的397例抑郁症患者进行焦虑自评量表（self-rating anxiety scale,SAS）、抑郁自评量表（self-rating depression scale,SDS）和one-back经典实验任务的检测.结果 SAS量表标准分[（51.81±11.50）分],SDS量表标准分[（62.94±13.06）分]与one-back任务的反应时[（590.27±213.96） ms]显著相关（r=0.125,P＜0.05;r=0.176,P＜0.01）,而且SAS量表标准分与SDS量表标准分的相关显著（r=0.682,P＜0.01）.回归分析结果发现,只有SDS量表得分能够显著预测one-back任务的反应时.结论 抑郁症患者的焦虑情绪和抑郁情绪都与认知功能有关,抑郁情绪是影响认知功能的主要因素.Objective To explore the effects of emotion on cognitive function in patients with depression.Methods Self-rating anxiety scale（SAS）,self-rating depression scale （SDS） and the typical one-back task were done by 397 patients with depression in Peking University Sixth hospital out-patient and hospitalization during 2012 June to 2013 October.Results Both of the SAS standard score （51.81 ± 11.50） and SDS standard score （62.94 ± 13.06） were significantly related （r=0.125,P〈0.05.r=0.176,P〈0.01） to the reaction time of one-back task （（590.27±213.96）ms）,and the correlation between SAS standard score and SDS standard score was significant （r=0.682,P〈0.01）.The results of regression analysis suggested that,only SDS score could predict the reaction time of one-back task.Conclusion The emotion of anxiety and depression in patients with depression are correlated with cognitive function,and the emotion of depression is the main factor to affect the cognitive function.

关 键 词：抑郁症 情绪 认知功能 焦虑 抑郁 

分 类 号：R749.4[医药卫生—神经病学与精神病学]