手足口病脑炎与其他病毒性脑炎比较分析  

Encephalitis caused by hand-foot-mouth disease complicated with encephalitis and other viruses:A comparative study

作　　者：肖伟强[1,2] 谭理连[3] 刘鸿圣 曾斯慧 李鹤虹 

机构地区：[1]广州医科大学 [2]广州市妇女儿童医疗中心放射科,广东广州510623 [3]广州医科大学第二附属医院放射科,广东广州510260

出　　处：《广州医科大学学报》2014年第5期25-27,共3页Academic Journal of Guangzhou Medical University

摘　　要：目的:探讨手足口病(HFMD)脑炎与其他非HFMD病毒性脑炎病灶的定位鉴别。方法:回顾性分析2011年2月至2012年12月广州市妇女儿童医疗中心收治的35例HFMD脑炎患者的临床资料,并与同期收治的35例非HFMD病毒性脑炎患者进行比较,观察两类患者病灶的定位特点。结果:HFMD脑炎的好发部位包括延髓、脑桥,非HFMD病毒性脑炎的好发部位包括基底节、大脑半球,两者比较,差异有统计学意义(P<0.05)。HFMD脑炎并发脊髓脊神经根炎较非HFMD病毒性脑炎多(P<0.05)结论:HFMD所致脑炎发生于脑桥、延髓较常见且特异度相对较高;脑部病灶同时并发脊髓病灶者对鉴别HFMD脑炎和非HFMD病毒性脑炎有意义。Objective：To investigate the lesion locations of encephalitis caused by hand-foot-mouth disease （HFMD） and other viral infections.Methods：The clinical data of 35 patients with HFMD encephalitis admitted in Guangzhou Women and Children Medical Center between February 2011 and December 2012 were retrospectively analyzed and compared with those from a contemporary cohort of 35 cases of non-HFMD viral encephalitis.The characteristics of the lesion locations in the two groups of patients were observed.Results：HFMD encephalitis frequently involved medulla and pons,compared with basal ganglia and cerebral hemisphere as did the non-HFMD viral encephalitis （ P〈0. 05 ） . Patients with HFMD encephalitis were more likely to have myeloradiculitis than those with non-HFMD viral encephalitis （P〈0.05）.Conclusion： Involvement of pons and medulla is more common and specific in HFMD encephalitis. Brain lesions complicated with myeloradiculitis are clinically significant to distinguish between HFMD and non-HFMD viral encephalitis.

关 键 词：手足口病 脑炎 脊髓脊神经根炎 MRI检查 

分 类 号：R72[医药卫生—儿科]