定量三维彩色多普勒超声联合血清β-HCG检查对胎盘功能低下的诊断  

The Value of Quantitative Three-dimensional Color Doppler Ultrasound Combined with β-HCG in Diagnosis of Placental Dysfunction

作　　者：黄燕玲[1] 他林坤[1] 徐飞[1] 袁娇[1] 

机构地区：[1]昆明医科大学第四附属医院超声科,云南昆明650021

出　　处：《昆明医科大学学报》2015年第5期58-60,共3页Journal of Kunming Medical University

基　　金：云南省应用基础研究基金资助项目(2013FZ192)

摘　　要：目的评估定量三维彩色能量多普勒超声(three-dimensional color power Doppler ultrasound,3D-CPD)联合β-HCG检查对胎盘功能低下的诊断价值.方法选择2012年5月至2014年3月在昆明医科大学第四附属医院接受产检的产妇368例,利用GE公司E8三维超声系统对胎盘的血管化指数(VI)、血流指数(FI)和血管化-血流指数(VFI)进行测量,同时利用化学发光法测定β-HCG水平.并在产后记录新生儿体长、体重和生命体征综合评分(Apgar评分).结果产后共有58例新生儿体重<2 500 g,为观察组,另外310例新生儿体重>2 500 g,为对照组.对照组VI、FI和VFI分别为(12.5±5.6)、(47.2±3.3)和(9.0±2.6),观察组为(10.2±4.8)、(40.6±4.1)和(4.2±1.7),差异具有统计学意义(P<0.05);观察组β-HCG水平为(29453.0±229.5)m IU/m L,中位数≥2.5 mom,对照组β-HCG水平为(8 442.6±47.2)m IU/m L,中位数<2.5mom,观察组β-HCG水平明显高于对照组(P<0.05);新生儿基本情况相比,观察组新生儿体长、体重和Apgar评分明显低于对照组(P<0.05).结论 3D-CPD联合β-HCG检查对胎盘功能异常具有重要的诊断价值,有利于围产期了解胎盘功能及估计胎儿预后.Objective To evaluate the diagnostic value of quantitative three-dimensional color Doppler ultrasound （3D-CPD） combined with β -HCG in diagnosis of placental dysfunction. Methods Three hundreds and sixty-eight parturients accepted prenatal screen in our hospital from May 2012 to March 2014 were selected, placental vascularization index （VI） , flow index （FI） and vascularization - blood index （VFI） were measured by GE＇s VOLUSON 730 three-dimensional ultrasound system, while β-HCG levels were measured by chemiluminescence. And the neonatal body length, weight and vital signs composite score （Apgar score） at birth were recorded. Results Placental pathological examination were taken at postpartum, a total of 58 cases were diagnosed as placental dysfunction, as the observation group, another 310 cases with normal placental function, as the control group. VI, FI and VFI in the control group were （12.5 ± 5.6） , （47.2 ± 3.3） and （9.0 ± 2.6） , while was （10.2 ± 4.8） , significant （P 〈0.05） ; （40.6 ± 4.1） and （4.2 ± 1.7） β -HCG level was ≥2.5mom in the observation group, in the observation group, the difference was statistically while was 〈2.5 morn in the control group, the observation group β -HCG levels were significantly higher （P 〈0.05） ; compared to the basic situation of the newborn, newborn body length, weight, and Apgar scores in the observation group were significantly lower than the control group （P 〈0.05） . Conclusions 3D-CPD combined with β -HCG check for abnormal placental function has important diagnostic value, in favor of perinatal understanding of placental function and fetal prognosis.

关 键 词：定量三维彩色能量多普勒超声 Β-HCG 胎盘功能异常 

分 类 号：R445.1[医药卫生—影像医学与核医学]