夫妇一方携带乙肝病毒对辅助生殖治疗中胚胎发育的影响  

The Impact of HBV Carried by One of a Couple on Embryonic Development in Assisted Reproductive Technology

作　　者：韩雪[1] 任春娥[1] 乔鹏云[2] 韩海艳[2] 张茂翔[2] 杨丽[1] 刘慧莹[1] 

机构地区：[1]潍坊医学院妇产科教研室,山东潍坊261053 [2]潍坊医学院附属医院生殖医学科

出　　处：《潍坊医学院学报》2015年第2期110-112,共3页Acta Academiae Medicinae Weifang

摘　　要：目的：探讨夫妇一方携带乙型肝炎病毒（ HBV）对辅助生殖治疗（ ART）中胚胎发育的影响。方法回顾性分析自2013年7月～2014年6月因女方不孕因素行体外受精联合胚胎移植技术（ IVF）治疗的188个周期，其中研究组为52例乙肝携带者，包含男方乙肝表面抗原（ HBsAg ）阳性39个周期，女方乙肝表面抗原（HBsAg）阳性13个周期，正常对照组136个周期。比较两组患者的受精率、卵裂率、优质胚胎率、冻存率之间的差异性。结果夫妇一方携带HBV较正常夫妇在ART中胚胎发育差异无统计学意义（P＞0．05）。结论夫妇一方携带HBV不影响辅助生殖治疗中的胚胎发育。Objective To investigate the impact of HBV carried by one of a couple on embryonic develop-ment in assisted reproductive technology .Methods An analysis of IVF-ET patients medical records of 188 cyclesfrom July 2013 to June 2014 in the center for female infertility was made .Among them,HBV carriers were 52 cycles,including the man HBs-Ag positive 39 cycles,the woman HBs-Ag positive 13cycles,while normal control group were 136 cycles. The fertilization rate ,cleavage rate ,high quality embryo rate and cryopreservation rate of the two groups were compared by embryo development criteria .Results There were no statistical difference between the two groups for the matched cri-teria（ P〉0.05） .Conclusion Either of the couple carried HBV has no effect on embryonic development in assisted re-productive technology .

关 键 词：乙肝病毒 辅助生殖治疗 胚胎发育 

分 类 号：R321.33[医药卫生—人体解剖和组织胚胎学]