CD146： the unveiling of a pro-angiogenic netrin receptor  

作　　者：Brad St Croix 

机构地区：[1]Tumor Angiogenesis Section. Mouse Cancer Genetics Program, National Cancer Institute (NCI). NIH. Frederick, MD 21702, USA

出　　处：《Cell Research》2015年第5期533-534,共2页细胞研究（英文版）

摘　　要：Netrin-1, a classic neuronal guidance cue, can promote angiogenesis under certain developmental and pathological conditions, but key receptors on vascular endothelium have remained elusive. A recent study published in Cell Research by Tu et al. reveals that CD146, an endothelial receptor of the immunoglobulin superfamily, binds netrin-1 with high affinity and may play an important role in regulating angiogenesis.

关 键 词：血管生成 受体 血管内皮细胞 免疫球蛋白超家族 血管发生 神经元 亲和性 人发 

分 类 号：Q463[生物学—生理学] Q516