低功率聚焦超声在乳腺增生症治疗中的作用  

Role of low power focused ultrasound in the treatment of hyperplasia of mammary

作　　者：杨炜[1] 冉立峰[1] 周崑[2] 金成兵[2] 朱辉[2] 王智彪[1] 

机构地区：[1]重庆医科大学生物医学工程学院、省部共建超声医学工程国家重点实验室培育基地、超声医学工程重庆市重点实验室,重庆400016 [2]重庆医科大学附属第二医院HIFU肿瘤治疗中心,重庆400010

出　　处：《重庆医科大学学报》2015年第3期446-449,共4页Journal of Chongqing Medical University

基　　金：重庆自然科学基金资助项目(编号:cstc2012jj A10083)

摘　　要：目的:探讨低功率聚焦超声治疗乳腺增生的可行性。方法:21例乳腺增生患者接受低功率聚焦超声治疗,治疗后1月,3、6、12个月进行临床随访和彩超声检查,对随访1年以上的的患者进行临床症状和超声影像学资料分析。结果:与术前相比,21例患者治疗后治疗后1个月、治疗后3个月、6个月和12个月疼痛评分和术前比较具有统计学差异(F=133.45,P=0.00);治疗后1个月增生腺体层厚度和术前比较差异无统计学意义(P=0.06),与随访时间短有关,治疗后3个月、6个月和12个月临床随访均有统计学意义(F=10.9,P=0.00);13例(13/21,62%)患者的乳腺影像报告数据系统分级下降。结论:低功率聚焦超声辐照乳腺增生组织患者止痛效果较好,为形成一种简易高效的疗法提供新途径。Objective：To explore the feasibility of low power focused ultrasound in the treatment of hyperplasia of mammary glands.Methods：Twenty-one patients diagnosed as hyperplasia of mammary glands accepted low power focused ultrasound treatment,and received examination of breast ultrasonography or mammography. All patients were followed up separately for 1,3,6,12 months after the treatment. Results：Pain score of twenty-one patients was collected at 1,3,6,12 months after treatment. There were statistical differences in pain score before and after the treatment（F=133.45,P=0.00）. There was no statistical difference in thickness of hyperplasia gland between one month after the treatment and before the treatment（P=0.06）due to short time of follow-up. There were statistical differences in thickness of hyperplasia gland between 3,6,12 months after the treatment and before the treatment（F=10.9,P=0.00）. Data system grading of breast image reports decline in 13 patients（13-21,62%）. Conclusion：It is effective to treat hyperplasia of mammary gland with low power focused ultrasound.

关 键 词：低功率 聚焦超声 乳腺增生 

分 类 号：R655.8[医药卫生—外科学]