培土生金方对慢性阻塞性肺疾病稳定期患者营养状态和免疫功能的影响  

Effect of Peitu Shengjin Recipe on Nutritional States and Immune Functions of Stable Phase COPD Patients

作　　者：宫静[1] 陈宁[1] 郝小梅[1] 李慧[1] 

机构地区：[1]广东省第二中医院呼吸科,广州510495

出　　处：《中国中西医结合杂志》2015年第5期534-536,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的探讨培土生金方对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)稳定期患者营养状态和免疫功能的影响。方法选择COPD稳定期患者62例,随机分为治疗组30例和对照组32例。对照组采用沙美特罗替卡松吸入剂(50/500μg)吸入治疗,1吸,1天2次;治疗组在对照组的基础上加用培土生金方治疗,每日1剂,3个月后观察2组慢性阻塞性肺疾病评估测试(COPD assessment test,CAT)评分,营养状况[BMI、皮褶厚度(TSF)、上臂中点肌肉周径(MAMC)、血清白蛋白、前白蛋白]及免疫功能(血清免疫球蛋白Ig A、Ig G、Ig M)。结果经药物治疗后,治疗组CAT评分较对照组下降更明显,差异有统计学意义(P<0.05);与对照组比较,治疗组BMI、TSF、MAMC及白蛋白、前白蛋白水平明显上升;免疫球蛋白Ig G、Ig M水平亦上升,差异有统计学意义(P<0.05)。两组Ig A水平比较,差异无统计学意义(P>0.05)。结论对于COPD稳定期患者,在西药常规治疗基础上加用培土生金方,能够使患者营养状态和免疫功能在一定程度上得到改善,同时更好的提高患者的健康相关生活质量。Objective To explore the effect of Peitu Shengjin Recipe （PSR） on nutritional states and immune functions of stable phase chronic obstructive pulmonary disease （COPD） patients. Methods Totally 62 stable phase COPD patients were randomly assigned to the treatment group （30 cases） and the control group （32 cases）. All patients inhaled Seretide （50/500 I^g）, twice per day. Besides, patients in the treatment group additionally received PSR, one dose per day. After three months of treatment, the COPD assessment test （CAT） score, the index of nutritional states [including body mass index （BMI）, thickness of skin fold （TSF）, mid-arm muscle circumference （MAMC）, serum albumin,serum prealbumin-I, and immune functions （including IgA, IgM, and IgG） were compared between the two groups. Results By the end of the treatment, the CAT score decreased more obviously in the treatment group than in the control group （P 〈0.05）. The improvement of BMI, TSF, MAMC, serum albumin, and serum prealbumin was better in the treatment group than in the control group （P 〈0.05）. IgM and IgG also increased more in the treat- ment group （P 〈 0. 05）. There was no statistical difference in IgA between the two groups （P 〉 0.05）. Conclusions Additionally use of PSR could improve nutritional states and immune functions of stable phase COPD patients to some extent. Meanwhile, it also could improve their health related quality of life.

关 键 词：慢性阻塞性肺疾病 培土生金方 营养状况 免疫功能 

分 类 号：R259[医药卫生—中西医结合]