不同胎龄早产儿潮气呼吸肺功能的测定及分析  

Measurement of tidal breathing pulmonary function in premature infants with different gestational ages

作　　者：吉玲[1] 马莉雅[1] 黄娜娜[1] 

机构地区：[1]郑州大学第三附属医院新生儿科,河南郑州450052

出　　处：《中国当代儿科杂志》2015年第5期449-452,共4页Chinese Journal of Contemporary Pediatrics

摘　　要：目的：探讨不同胎龄早产儿潮气呼吸肺功能的特点。方法根据胎龄将75例早产儿分为3组：〈32周组、32-33＋6周组、34-36＋6周组；55例39-40周的足月儿作为对照组。生后3-5 d测定各组潮气呼吸肺功能，并在纠正胎龄40周时对各组再次进行潮气呼吸肺功能的测定。结果生后3-5 d时，3个早产儿组的吸气时间（tI））、达峰时间（TPEF）、达峰时间比（TPEF/tE）均低于对照组（P〈0.05）；且显示胎龄越低，潮气呼吸肺功能指标值越低的倾向。纠正胎龄40周时，3个早产儿组的TPEF、TPEF/tE仍明显低于对照组（P〈0.05）。结论新生儿潮气呼吸肺功能受胎龄的影响，早产儿有明显的潮气呼吸肺功能受损，胎龄越小，潮气呼吸肺功能受限越明显。ObjectiveTo investigate the characteristics of the tidal breathing pulmonary function in premature infants with different gestational ages.MethodsA total of 75 premature infants were classified into three groups according to their gestational ages： 〈32 weeks, 32-33＋6 weeks and 34-36＋6 weeks. Fifty-ifve full-term infants （39-40 weeks group） were selected as the control group. All infants were given the tidal breathing pulmonary function test at 3-5 days after birth. Moreover, all infants were given the tidal breathing pulmonary function test again at 40 weeks of the corrected gestational age.ResultsAt 3-5 days after birth, the three groups of premature infants had signiifcantly lower inspiratory time, time to peak tidal expiratory lfow （tPTEF）, and ratio of tPTEF to total expiratory time （tPTEF/tE） than the control group （P〈0.05）. The parameter values of the tidal breathing pulmonary function were lower when the gestational age was lower. Even at 40 weeks of the corrected gestational age, the three groups of premature infants still had signiifcantly lower tPTEF and tPTEF/tE than the control group （P〈0.05）.ConclusionsThe tidal breathing pulmonary function of neonates is inlfuenced by the gestational age. The tidal breathing pulmonary function of premature infants is obviously impaired, and the lower the gestational age, the more obvious the impairment.

关 键 词：肺功能 胎龄 早产儿 

分 类 号：R722.6[医药卫生—儿科]