冠状动脉不同钙化程度的临床特征分析  

The clinical characteristics of different degree of coronary artery calcification

作　　者：卿平[1] 苏文君[1] 徐瑞霞[1] 郭远林[1] 孙静[1] 郭悦[1] 李琳[1] 

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外心血管病医院心内科,100037

出　　处：《心肺血管病杂志》2015年第5期367-370,共4页Journal of Cardiovascular and Pulmonary Diseases

基　　金：院所青年基金项目(2014-F06 0001100)

摘　　要：目的：对冠状动脉不同钙化程度的临床特征进行分析。方法：收集本院2011年2月至2012年5月间,具有CT结果及完整临床资料的患者499例,根据冠状动脉钙化积分按CT结果分为轻中度钙化组238例,重度钙化组88例,并对此类患者的临床特征及影响钙化的因素进行系列分析。结果：与轻中度钙化组相比,重度钙化组患者年龄较大,男性居多,且血红蛋白浓度显著降低[（146.85±16.93）vs.（135.94±15.61）g/L,P=0.005],Logistic回归分析显示年龄（OR=1.10,95CI：1.06-1.14,P〈0.001）、性别（OR=0.21,95%CI：0.08-0.059,P=0.003）、血红蛋白浓度（OR=0.97,95%CI：0.95-0.99,P=0.005）均为CAC程度的独立预测因子。结论：本研究结果显示高龄、男性及血红蛋白浓度低是CAC严重程度的独立预测因子。Objective： The aim of this study was to investigate the clinical features of different degree of coronary artery calcification（ CAC）. Methods： A total of 499 consecutively admitted patients from Feb 2011 to May 2012 in Fu Wai Hospital were analyzed. All patients had received coronary computed tomography angiography（ CCTA） and the patients who had CAC divided into two groups based on the results of coronary calcium score. The clinical information included calcification risk factors,and the difference of clinical characteristic was analyzed between the mild-moderate and the severe groups. Results： Patients in severe group had elevated age（ P〈0. 001）. Patients with mild-moderate CAC had significantly elevated hemoglobin levels compared with those with severe CAC [（ 146. 85 ± 16. 93） vs.（ 135. 94 ± 15. 61） g / L,P = 0. 005]. In the multivariate analysis,hemoglobin（ OR = 0. 97,95% CI： 0. 95 - 0. 99,P = 0. 005）,age（ OR = 1. 10,95C1： 1. 06 - 1. 14,P〈0. 001） and gender（ OR = 0. 21,95% CI： 0. 08 - 0. 0. 59,P = 0. 003） appeared as independent factors predictive of the degree of CAC. Conclusion： We demonstrated that the age,gender and hemoglobin were valuable independent predictors of CAC.

关 键 词：冠状动脉钙化 钙化积分 临床特征 年龄 性别 血红蛋白浓度 

分 类 号：R54[医药卫生—心血管疾病]