非发酵菌在重症监护病房患者中感染分布及其耐药性研究  

Study on distribution and drug resistance of nonfermenters infection in ICU patients

作　　者：方寅飞 徐浩[1] 冯胜春[1] 

机构地区：[1]浙江省金华市中心医院,浙江金华321000

出　　处：《中国消毒学杂志》2015年第5期452-454,共3页Chinese Journal of Disinfection

摘　　要：目的研究临床送检标本中非发酵菌分离率及其耐药特点,为控制非发酵菌感染提供参考。方法采用病原学标本分离鉴定技术和药敏试验方法,对送检病原学标本进行检测与分析。结果某医院在2013年度从重症监护病房患者送检标本中,共检出非发酵菌264株,主要分离自痰液和引流液标本,构成比分别为47.7%和12.9%。在检出的非发酵菌中,居前3位的是铜绿假单胞菌、鲍曼不动杆菌和嗜麦芽假单胞菌,构成比依次为38.3%、29.5%和22.3%。临床分离的非发酵菌对常用抗菌药物均有不同程度的耐药,并检出多重耐药菌株。结论非发酵菌群是重症监护病房患者医院感染常见病原菌,其耐药现象严重,应加强耐药性监测,合理选用抗菌药物。Objective To study isolated rate of nonfermenters and drug resistance characteristics in specimens from pa- tients in ICU,to provide reference for the control of nonfermenters infection development. Methods Pathogen separation and identification technique and drug sensitivity test were used to test and analyze etiology specimens from ICU hospitalized patients in a hospital. Results There were 264 strains of nonfermenters detected out from 1CU patients specimens in 2013, mainly isolated from sputum and drainage fluid specimens,the constituent ratio were 47.7% and 12. 9% respectively. In the detected nonfermenters,the top three were Pseudomonas aeruginosa,Acinetobacter baumannii and Stenotrophomonas malto- philia, the constituent ratio were 38. 3%, 29. 5% and 22. 3%. Drug resistance of clinical isolated nonfermenters to com- monly used antimicrobial agents had different degree, and multi - drug resistance strains were detected out. Conclusion Nonfennenters were common pathogen of hospital infection in ICU, clinicians should strengthen the reasonable selection of antimicrobial agents and resistance surveillance.

关 键 词：非发酵菌 重症监护病房 医院感染 多重耐药 监测 

分 类 号：R378[医药卫生—病原生物学]