产气肠杆菌临床分布及耐药性检测  

The clinical distribution and drug-resistance detection of Enterobacter aerogenes

作　　者：周蕾[1] 盛萍萍[1] 林艳红[1] 陶映[1] 应利君[1] 

机构地区：[1]绍兴市人民医院浙江大学绍兴医院,浙江绍兴312000

出　　处：《中国消毒学杂志》2015年第5期468-469,472,共3页Chinese Journal of Disinfection

摘　　要：目的了解医院感染产气肠杆菌临床分布及耐药情况,为临床用药提供参考。方法采用临床标本检验和药敏试验方法,对某医院2013年住院患者送检标本进行病原菌检测和药敏试验。结果从患者送检标本中分离到产气肠杆菌111例,主要分布于神经外科、肝胆外科和重症医学科的痰液和胆汁中。临床分离的产气肠杆菌对头孢西丁和头孢唑啉几乎100%耐药,对第四代头孢类比较敏感;对氨曲南产生耐药,但对亚胺培南和美罗培南等碳青霉烯类均比较敏感。结论该医院分离的产气肠杆菌耐药现象日益严重,对高危病区应完善和落实各项预防措施,严格无菌操作,加强对易感患者的监测。Objective To investigate the clinical distribution and drug - resistance of Enterobacter aerogenes in our hospi- tal. Methods Clinical sampling detection and drug sensitive test were used to analyze the inpatients＇ samples in 2013 in the hospital, so as to provide leference for clinic. Results The 111 cases of Enterobacter aerogenes were collected which were mainly isolated from patient＇s sputum and bile from department of neurosurgery, hepatobiliary surgery and department of ICU. The resistance rate of Enterobacter aerogenes to cefoxitin and cefazolin were almost 100%. And it was sensitive to general fourth cephalosporin,resistant to aztreonam,but sensitive to imipenem and meropenem. Conclusion Drug - resist- ance of Enterobacter aerogenes is serious. We should complete the prevention management of high risk department, strength- en antiseptic operation and the surveillance of susceptible patients.

关 键 词：产气肠杆菌 医院感染 临床分布 耐药性 监测 

分 类 号：R378[医药卫生—病原生物学]