抗菌药物围术期应用联合术中聚维酮碘宫腔擦洗预防剖宫产感染的研究  

Clinical study on combined therapy of intrauterine scrub with Povidone-iodine and perioperative application of antibacterials for prevention of infections after cesarean

作　　者：唐未坤[1] 张峰[1] 汪洋[1] 

机构地区：[1]天津市职业病防治院妇产科,天津300011

出　　处：《中华医院感染学杂志》2015年第12期2748-2749,2807,共3页Chinese Journal of Nosocomiology

基　　金：天津市卫生局重点规划基金资助项目(TW-2012C027)

摘　　要：目的探讨剖宫产手术前使用抗菌药物和聚维酮碘宫腔擦洗对于预防剖宫产术后感染影响,以降低产妇剖宫产感染率。方法对医院2012年12月-2013年12月进行剖宫产分娩的120例产妇进行研究,将其随机分为手术前单纯应用抗菌药物组60例(对照组)和手术前使用抗菌药物联合聚维酮碘宫腔擦洗组60例(观察组),两组患者在手术后均进行静脉滴注甲硝唑3d,观察所有产妇手术后各项体征指标,数据均采用SPSS11.0统计软件进行分析处理。结果观察组产妇剖宫产术后发热发生率、切口感染率分别为95.00%及3.33%,对照组分别为100.00%及28.33%,两组比较差异有统计学意义(P<0.05);两组产妇手术后血常规白细胞计数比较,差异有统计学意义(P<0.05)。结论手术前使用抗菌药物联合聚维酮碘宫腔擦洗对于预防产妇剖宫产术后感染率的降低,有一定临床价值,值得临床使用。OBJECTIVE To investigate the use of preoperative antibacterials and povidone‐iodine scrub for the prevention of infections after cesarean .METHODS Totally 120 patients undergoing cesarean in Dec .2012 to Dec . 2013 were studied and randomly divided into the control group （n= 60 , single application of preoperative antibacterials） and the observation group （n=60 ,combined therapy of preoperative antibacterials and povidone‐iodine scrub） .Both groups of patients received intravenous infusion of metronidazole for three days after opera‐tion .All patients were observed for each physical sign and the software SPSS 11 .0 was used for statistical analysis of data .RESULTS The incidence of fever and the rate of incision infections after cesarean was 95 .00% ,3 .33% in the observation group and 100 .00% ,28 .33% in the control group ,the difference was significant （P〈 0 .05） . There was significant difference in postoperative routine WBC between the two groups （P〈0 .05） .CONCLUSION The use of antibacterials before operation combined with povidone‐iodine intrauterine scrub for the prevention of infections after cesarean has clinical value and is worthy of clinical use .

关 键 词：抗菌药物 聚维酮碘 剖宫产 宫腔擦洗 术后感染 

分 类 号：R978.1[医药卫生—药品]