有机立体化学构型判断及互换  

Judgement Configuration and Mutual Conversion Techniques in Organic Stereochemistry

作　　者：庞韬[1] 吴根华[1] 

机构地区：[1]安庆师范学院化学化工学院,安徽安庆246011

出　　处：《安庆师范学院学报（自然科学版）》2015年第2期134-136,共3页Journal of Anqing Teachers College(Natural Science Edition)

基　　金：安徽省级自然科学研究重点项目(KJ2014A141)

摘　　要：通过举例介绍了有机立体化学中透视式和Fischer投影式中手性碳原子的R/S构型最基本判断法则。在立体化学的重点和难点——Newman投影式、透视式与Fischer投影式之间的相互转换等方面,针对空间想象能力较薄弱的初学者,在遵循该法则的基础上,结合教学实践及教学实例,引导学生发现规律,探讨总结出一套有效的经验方法。使学生不再依赖分子模型的辅助,准确地实现分子各种立体结构式之间的相互转换,有助于同学们理解烯烃的亲电加成反应、卤代烃和醇的消除反应的立体化学并可以解决相关问题。By exemplification, the author discussed the fundamental judgment rules of the R、S configuration of chiral carbon atom in organic stereochemistry＆#39;s perspective and Fischer＆#39;s Projection.Using this rule, it can help students learn and summary the effective method on the mutual transformation of Newman＆#39;s Projection, perspective and Fisher＆#39;s Projection in stereochemistry.As a result, students can transfer the dimensional structure of molecules and will no longer rely on the auxiliary of molecular models . This is beneficial to students to understand and solve the relevant questions in stereochemistry , such as the electrophilic addition reaction of olefins, elimination reaction of halogenated hydrocarbon and alcohol.

关 键 词：有机立体化学 转换 S构型 Newman投影式 FISCHER投影式 

分 类 号：O621[理学—有机化学]