腹腔镜手术对合并全身炎性反应综合征阑尾炎患者术后血清C反应蛋白及临床指标的研究  

Effect of laparoscopic appendectomy on appendicitis patients combined SIRS

作　　者：朱乃海[1,2] 

机构地区：[1]江苏省南京市第一医院浦口分院 [2]浦口中心医院普通外科,211800

出　　处：《检验医学与临床》2015年第11期1538-1539,共2页Laboratory Medicine and Clinic

基　　金：南京市科技局资助项目(20130322)

摘　　要：目的比较腹腔镜阑尾切除术(LA)和开腹阑尾切除术(OA)治疗合并全身炎性反应综合征(SIRS)阑尾炎患者术后各临床指标及血清C反应蛋白(CRP)的差异。方法该院2012年6月至2014年4月收治的合并SIRS阑尾炎患者82例,随机分为LA组43例,OA组39例,比较2组患者术后CRP水平、SIRS症状改善时间、腹腔引流量、腹腔脓肿及切口感染。结果术后第1天CRP水平达最高峰,OA组显著高于LA组,差异有统计学意义(P<0.05),第3天CRP水平均下降,但OA组仍高于正常水平,LA组下降至正常水平,2组比较差异有统计学意义(P<0.05)。术后LA组患者的SIRS症状改善时间、腹腔引流量、腹腔脓肿及切口感染率均优于OA组,差异有统计学意义(P<0.05)。结论 LA具有彻底清除腹腔感染灶、迅速缓解SIRS症状、减少并发症等优点。Objective To compare the difference of postoperative serum c-reactive protein level and clinical in- dicators in appendicitis patients combined SIRS by laparoscopic appendectomy（LA） and open appendectomy（OA） treatment. Methods From June 2012 to April 2014,82 appendicitis patients combined SIRS were randomly divided into LA group（43 patients） and OA group（39 patients）, compared postoperative serum CRP levels, SIRS symptoms improved time, abdominal volume of drainage, abdominal abscess and infection of incision between two groups. Results The level of CRP in serum of two groups rised to the highest in the first day after operation. The level of OA group is significantly higher than that of LA group （P〈0.05）. The serum CRP level of two groups decreased in the third day, but the level of OA group is higher than that of normal, LA group dropped to normal levels, there were statistical difference between two groups （P〈0. 05） ）on SIRS symptoms improved time,abdominal volume of drainage, abdom- inal abscess and infection of incision rate,LA group were superior to OA （P〈0.05）. Conclusion LA has the charac- ter of dislodge abdominal cavity infection focal thoroughly, relieve SIRS rapidly and less complications.

关 键 词：腹腔镜 阑尾切除术 全身炎性反应综合征 

分 类 号：R59[医药卫生—内科学]