第二代Amplatzer动脉导管未闭封堵器经股动脉逆行插管行室间隔缺损封堵术疗效评价  

Efficiency evaluation of retrograde transcatheter closure of ventricular septal defects using amplatzer duct occluderⅡ

作　　者：张戈军[1] 徐仲英[1] 蒋世良[1] 赵世华[1] 凌坚[1] 宋会军[1] 万俊义[1] 

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外心血管病医院心血管疾病国家重点实验室介入放射科,北京100037

出　　处：《临床荟萃》2015年第6期601-604,共4页Clinical Focus

摘　　要：目的探讨第2代Amplatzer动脉导管未闭封堵器（ADOⅡ）经股动脉逆行插管行室间隔缺损封堵术疗效。方法室间隔缺损患者5例,年龄5-53岁,经胸超声心动图显示室间隔缺损为4-6mm。第二代Amplatzer动脉导管未闭封堵器经股动脉逆行插管行室间隔缺损封堵术,术后24小时、6个月及1年行超声心动图、X线平片及心电图进行随访。结果造影显示室间隔缺损3-5mm,肺动脉压为14-28mmHg（1mmHg=0.133kPa）。5例封堵器植入均获得成功,术后即刻2例存在微量残余分流,术后24小时5例室间隔缺损均完全闭合。随访中未见室间隔缺损再通及其他并发症。结论对于部分有选择的病例,应用ADOⅡ经股动脉逆行插管行室间隔缺损封堵术安全可行,可简化操作流程。ABSTRACT：Objective To evaluate the efficiency of retrograde transcatheter closure of ventricular septal defects （VSD）using the amplatzer duct occluder Ⅱ.Methods There were 5 cases with VSD,with age range from 5 to 53 years old.Before intervention,each patient revealed the diameter of VSD range from 4 to 6 mm.All patients were treated by retrograde transcatheter closure using the amplatzer duct occluder Ⅱ.Echocardiography,electrocardiogram and X-ray examination were done at 24 hours,6 months and 1 year after the procedures as follow-up.Results Left ventricle angiography revealed that the diameter of VSD range from 3-5 and the mean pulmonary artery pressure range from 14-28 mmHg.All five patients were treated successfully by the method.Trivial residual shunt was found in 2 cases after the procedures immediately and all VSD were closed at 24 hours after the procedures.There were no recanalization and complication during the follow-up.Conclusion For some selected patients,retrograde transcatheter closure of VSD using the amplatzer duct occluder Ⅱ was safe and efficient.This method could simplify the procedure of transcatheter closure of VSD.

关 键 词：室间隔缺损 导管插入术 心间隔封堵装置 

分 类 号：R541.1[医药卫生—心血管疾病]