呼和浩特地区RhD阴性献血者表型库的建立及应用  

Establishment and application of the phenotype database of negative RhD blood donors in Hohhot

作　　者：尚锦青[1] 贾雯婷[1] 苏仁娜[1] 崔丽敏[1] 

机构地区：[1]内蒙古自治区血液中心,内蒙古呼和浩特010070

出　　处：《国际检验医学杂志》2015年第11期1550-1551,共2页International Journal of Laboratory Medicine

摘　　要：目的了解该地区RhD阴性献血者表型分布,建立RhD阴性表型数据库。方法 RhD初筛阴性的554份标本采用间接抗球蛋白试验确认。排除重复献血者后,剩余标本为366份,对其进行Rh血型表型分析。结果 RhD阴性表型分布特征为ccdee(56.28%)>Ccdee(29.51%)>ccdEe(7.38%)>CcdEe(3.55%)>CCdee(3.01%)>ccdEE(0.27%),未检出CcdEE、CCdEe、CCdEE型。结论建立RhD阴性表型数据库,有利于为RhD阴性及含有Rh同种抗体的患者提供相匹配血液,满足其急救用血,且对科学管理RhD阴性血源和合理运用RhD阴性血液有重要意义,为该地区尤其蒙古族RhD阴性血型积累了资料。Objective To understand the phenotype distribution of negative RhD blood donors in local region ,and to establish negative RhD phenotype database .Methods A total of 554 specimens screened firstly as negative RhD were confirmed by indirect antiglobulin test .Repeat donors were excluded ,the remaining specimens were 366 cases ,which were analyzed the phenotype of Rh blood .Results Distribution characteristics of negative RhD phenotype was ccdee （56 .28% ） 〉 Ccdee （29 .51% ） 〉 ccdEe （7 .38% ）〉 CcdEe （3 .55% ）〉 CCdee （3 .01% ）〉 ccdEE （0 .27% ） ,there were no CcdEE ,CCdEe ,CCdEE detected .Conclusion The establishment of Negative RhD phenotype database is help for providing matching blood for persons with negative RhD blood or same antibody blood ,and meeting the emergency blood usage ,it′s important for scientific management and reasonable application of negative RhD blood ,and accumulate data for then negative RhD blood of the local area ,especially for Mongolian .

关 键 词：RHD 阴性 表型 数据库 

分 类 号：R446.6[医药卫生—诊断学]