中药药效物质基础研究进展  

Study Progress on Pharmacodynamic Material Basis of Chinese Materia Medica

作　　者：郭倩[1] 田成旺[2] 任涛[2] 张铁军[2] 

机构地区：[1]天津医科大学药学院,天津300070 [2]天津药物研究院,天津300193

出　　处：《世界科学技术-中医药现代化》2015年第3期648-654,共7页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金委青年基金项目(81001627):应用仿生技术研究藏茵陈抗肝炎药效物质基础;负责人:田成旺

摘　　要：中药药效物质基础研究是中药现代研究的关键点之一,是阐释中药整体功效及其作用本质的核心环节,是中药安全、有效和质量控制的重要基础。但由于中药多成分和药效作用的复杂性,以及中药各有效成分的协同作用,使得中药药效物质基础的阐明成为难题,制约着中医药的现代化进程。因此,中药药效物质基础目前已受到学术界的广泛重视,许多专家学者对此进行了大量的研究和实践。本文通过回顾、分析近年来中药药效物质基础研究的相关文献,综述了中药药效物质基础的内涵、研究思路和方法,并探讨了目前研究中存在的一些问题,以期对中药药效物质基础研究提供参考。Study on pharmacodynamic material basis of Chinese materia medica （CMM） is one of the key points of CMM modern research. It is also the core of ascertaining the overall efficacy and the function essence of CMM. It is an important basis for the safety, efficacy and quality control of CMM. However, since the multiple components, complex medical effects and interactions among effective components of CMM, the clarification of pharmacodynamic material basis has become a difficult question, which restricts the CMM modernization. Therefore, pharmacodynamic material basis of CMM has received widespread attention in the academic field. Many experts and scholars have done a lot of research and practice on this area. This article analyzed relevant literatures about pharmacodynamic material basis researches of CMM, and reviewed connotation, research thoughts and methods of CMM. It discussed some existing problems in current studies. The goal was to provide references for pharmacodynamic material basis of CMM.

关 键 词：中药药效物质基础 内涵 思路 方法 研究进展 

分 类 号：R285[医药卫生—中药学]