右美托咪定用于腹腔镜胆囊切除术中的临床观察分析  

Dexmedetomidine for clinical observation and analysis of laparoscopic cholecystectomy in the

作　　者：雷兴阳[1] 郭继东[1] 祝兵[1] 

机构地区：[1]东台市人民医院麻醉科,江苏东台224200

出　　处：《中外医疗》2015年第3期126-127,共2页China & Foreign Medical Treatment

摘　　要：目的分析右美托咪定用于腹腔镜胆囊切除术中的临床效果。方法收集2012年1月—2013年12月该院收治的80例腹腔镜胆囊切除术患者临床资料,随机分为对照组与观察组,各40例。对照组气管插管后术前10 min给予静脉泵注生理盐水,观察组气管插管后术前10 min给予静脉泵注右美托咪定,均以丙泊酚维持麻醉,对比两组患者临床应用效果。结果与入室时对比,观察组患者HR、DBP、SBP在切皮及拔管对比,差异不明显,对照组SBP、DBP明显升高,HR明显增快,差异有统计学意义(P<0.05)。观察组患者丙泊酚维持用量明显少于对照组,拔管时间短于对照组,术后躁动发生率低于对照组,差异有统计学意义(P<0.05)。结论于腹腔镜胆囊切除术中应用右美托咪定,具有明显的安全性与有效性,维持稳定的血流动力学,患者术后苏醒迅速,值得临床推广。Objective analysis of dexmedetomidine for laparoscopic cholecystectomy in the clinical effect of surgery. Methods from 2012 to 2013December, 01 months in our hospital 80 cases of laparoscopic cholecystectomy in patients with clinical data, were randomly divided into control group and observation group, 40 cases in each. The control groupafter intubation preoperatively to 10 min intravenous pump infusion of saline,the observation group after intubation preoperatively to 10 m in intravenouspump in-fusion of dexmedetomidine, propofol maintained anesthesia with,compared two groups of patients with clinical application effect. Results compared with baseline, the patients in observation group were H R, DBP, SB P in the skin incision and extubation com-parison, the difference is not obvious, the control group S B P, DBP was significantly increased, H Rsignificantly increased （P〈0.05）. Patients in the observation group propofoldosage was less than the control group, the extubation time was shorter than the control group, the postoperative agitation rate lower than that of the control group （P〈0.05）. Conclusion in laparoscopic cholecys-tectomyapplications of dexmedetomidine in operation, with safety and effectiveness of the obvious, maintain the stability of hemo-dynamics, patients quickly regained consciousness after the surgery, is worth the clinical promotion.

关 键 词：右美托咪定 腹腔镜胆囊切除术 临床观察 

分 类 号：R657.4[医药卫生—外科学]