依沙吖啶羊膜腔内注射配伍口服米非司酮对疤痕子宫引产的临床效果  

Clinical effect of ethacridine injection intra amniotic cavity combined oral mifepristone on Scar uterus induced labor

作　　者：刘秀玲 贺全勤 

机构地区：[1]驻马店市中心医院妇二科,河南驻马店460000

出　　处：《中外医疗》2015年第5期111-112,共2页China & Foreign Medical Treatment

摘　　要：目的分析沙吖啶羊膜腔内注射配伍口服米非司酮在疤痕子宫中期妊娠引产中的应用情况。方法选取2012年6月—2014年6月该院收治的100例中期妊娠要求引产的疤痕子宫患者作为研究对象,采用数字随机法将患者分为对照组和观察组,对照组取依沙吖啶羊膜腔内注射引产,观察组取依沙吖啶羊膜腔内注射配伍口服米非司酮引产,记录引产时间和产后出血量,记录、宫颈成熟有效率、1次引产成功率、胎盘残留和粘连率。结果观察组引产中宫颈成熟有效率为96.0%显著高于对照组76.0%,差异有有统计学意义(P<0.05)。观察组注药至宫缩时间、宫缩至胎儿娩出时间、总产程、产后出血量分别为(29.63±5.26)h、(6.01±3.26)h、(7.11±2.67)h、(65.29±14.20)m L均显著低于对照组差异有统计学意义(P<0.05)。观察组胎盘残留和胎盘粘连率分别为12.0%、2.0%均显著低于对照组44.0%、26.0%,差异有统计学意义(P<0.05)。结论依沙吖啶羊膜腔内注射配伍口服米非司酮引产,可促使宫颈成熟,缩短总产程,降低疤痕子宫产后胎盘残留率。Objective To observe the application of ethacridine injection intra amniotic cavity combined oral mifepristone on in-duction of mid-term pregnancy of scarred uterus. Methods 100 cases of mid pregnancy labor requirements select Hospital of uter-ine scar patients as the research object, were randomly divided into control group and observation group, control group took amni-otic cavity injection of ethacridine in induction of labor, the observation group took ethacridine intra amniotic injection combined with mifepristone, recorded the induction time and the amount of postpartum hemorrhage, cervical ripening efficiency for 1 time, the successful rate of induced labor, residue of placenta and the adhesion rate. Results Labor induction in observation group, cer-vical mature efficiency of 96%was significantly higher than that of control group 76%, differences were statistically significant （ P〈0.05）. Injection to contraction time, uterine contraction to delivery time, total labor time, postpartum hemorrhage in observation group were （29.63±5.26） h, （6.01±3.26） h, （7.11±2.67） h, （65.29±14.20） ml, were significantly lower than control group, difference was statistically significant （P〈0.05）. The observation group of residue of placenta and placenta adhesion rates 12% and 2%, were significantly lower than control group 44%, 26%, difference was statistically significant（P〈0.05）. Conclusion Rivanol amniotic cav-ity injection of oral mifepristone compatibility, can promote cervical ripening, reduce birth process, reduce scar uterus postpartum placenta remnants rate.

关 键 词：疤痕子宫 引产 依沙吖啶 米非司酮 引产成功率 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]