血栓抽吸联合替罗非班用于急性心肌梗死患者PCI术中的疗效分析  

Analysis of the Effect of Thrombus Aspiration Combined with Tirofiban on Acute Myocardial Infarction with PCI

作　　者：宋荣刚[1] 李明[1] 任静 

机构地区：[1]山东省济南市第五人民医院,山东济南250022 [2]滨州市复退军人医院,山东济南256600

出　　处：《中外医疗》2015年第8期12-14,共3页China & Foreign Medical Treatment

摘　　要：目的探讨急性心肌梗死患者经皮冠状动脉介入治疗(PCI)中联合应用血栓抽吸和替罗非班的效果。方法随机选取该院201 1年1月—2014年6月间收治的急性心肌梗死患者84例,均行PCI术,随机分为对照组(应用替罗非班)和观察组(同时应用替罗非班和血栓抽吸),比较两组治疗效果。结果观察组患者PCI术后冠脉造影TIMI 3级血流获得率明显高于对照组,术后3个月患者心功能优于对照组;随访6个月患者术后心血管事件发生率(0.0%)明显低于对照组(14.29%),差异有统计学意义(P<0.05)。结论 急性心肌梗死介入治疗中联合应用血栓抽吸和替罗非班效果显著,值得临床推广应用。Objective To investigate the effect of thrombus aspiration combined with tirofiban on acute myocardial infarction（AMI） with percutaneous coronary intervention （PCI）. Methods 84 cases with AMI underwent PCI in our hospital from January 2011 to June 2014 were randomly divided into the control group treated by tirofiban and the observation group treated by tirofiban and thrombus aspiration. And the treatment effect was compared between the two groups. Results The coronary angiography after PCI showed that, a greater percentage of TIMI 3 flow was achieved in the observation group compared with the control group; the ob-servation group had better cardiac function 3 months after the surgery than the control group; the incidence of postoperative car-diovascular event of the observation group was much lower than that of the control group showed by the 6-month follow-up（0.0%vs. 14.29%）, the differences were statistically significant （P〈0.05）. Conclusion The combined application of thrombus aspiration and tirofiban to AMI with PIC has significant effect, which is worthy of clinical application and promotion.

关 键 词：血栓抽吸 替罗非班 急性心肌梗死 

分 类 号：R54[医药卫生—心血管疾病]