探析糖化血红蛋白和尿微量白蛋白联合检测在2型糖尿病肾病早期诊断中临床应用价值  

Clinical Value of Combined Detection of Glycosylated Hemoglobin and Microalbuminuria Applied to the Early Diagnosis of Type 2 Diabetic Nephropathy

作　　者：周静姝[1] 

机构地区：[1]吉林市吉化总医院检验科,吉林吉林132021

出　　处：《中外医疗》2015年第8期194-196,共3页China & Foreign Medical Treatment

摘　　要：目的探讨糖化血红蛋白(HbA1c)和尿微量白蛋白(U-mAlb)联合检测在2型糖尿病肾病早期诊断中临床应用价值。方法抽取该院2012年6月—2013年12月来该院就诊98例2型糖尿病患者,其中糖尿病肾病50例(观察1组)、2型糖尿病非肾病48例(观察2组),随机抽取该院健康体检中心2013年6月—2013年9月间正常健康体检者82例(对照组)为研究对象,检测糖化血红蛋白和尿微量白蛋白的含量,并对结果进行比对。结果观察1组和2组的HbAlc、U-mAlb明显高于对照组,差异有统计学意义(P<0.01);病程的长短与HbMc、U-mAlb指标有密切关系,病程越长HbAlc、U-mAlb指标越高;HbAlc越高U-mAlb指标也就越高。结论 糖化血红蛋白和尿微量白蛋白联合检测为糖尿病肾病早期诊断、治疗提供可靠科学依据。Objective To investigate the glycated hemoglobin （HbAlc） and microalbuminuria （U-mAlb） clinical nephropathy in type 2 diabetes diagnosis value of combined detection. Methods Extraction hospital in June 2012 - December 2013 to our hospi- tal98 cases of type 2 diabetes, including diabetic nephropathy in 50 cases （observation group）, type 2 diabetes, 48 cases of non- renal disease （observation group 2）, random decimation of our hospital health examination center between June 2013 - September 2013 82 cases of normal healthy persons （control group） for the study, glycated hemoglobin and urine albumin levels, and the re- sults were compared. Results Group 1 and Group 2 HbAlc, U-mAlb significantly higher, the difference was statistically significant （P〈0.01）; the longer the length of the course and HbAlc, U-mAlb index is closely related to the course HbAlc, U-mAlb index higher; HbAlc higher U-mAlb index is higher. Conclusion glycated hemoglobin and microalbuminuria joint detection for early di- agnosis of diabetic nephropathy, treatment with reliable scientific basis.

关 键 词：糖化血红蛋白 尿微量白蛋白 2型糖尿病 糖尿病肾病 

分 类 号：R446.1[医药卫生—诊断学]