不同程度心力衰竭老年患者血浆NT-proBNP浓度变化及预后分析  

Analysis of the Changes of Plasma NT-pro BNP Concentration in Elderly Patients with Heart Failure of Different Severity and the Prognosis

作　　者：李明[1] 宋荣刚[1] 辛梅[1] 

机构地区：[1]山东省济南市第五人民医院心内科,山东济南250022

出　　处：《中外医疗》2015年第10期5-6,9,共3页China & Foreign Medical Treatment

摘　　要：目的探究不同程度心力衰竭老年患者血浆NT-pro BNP浓度变化及预后分析。方法测试2012年3月—2013年12月期间该院收治的206心力衰竭患者不同阶段的血浆NT-pro BNP浓度,把发生心绞痛、心力衰竭复发和死亡患者作为死亡组;没有发生上述病症的患者作为存活组,对两组患者血浆的浓度变化和预后情况进行分析。结果通过对数据分析结果显示:病因不同的患者,血浆NT-pro BNP浓度也不尽相同。出现心血管疾病的患者左室射血分数较未出现心血管疾病的患者相比较低,差异有统计学意义(P<0.05)。数据显示死亡组患者入院阶段的血浆浓度明显高于存活组。结论由数据分析发现,通过分析得出存活组血浆浓度低于死亡组,心力衰竭患者浓度不断升高,需要注意预后情况,在临床中有很大的研究价值。Objective To explore the changes in plasma NT-proBNP concentration in elderly patients with heart failure of different severity and the prognosis. Methods The plasma NT-proBNP concentration was measured in 206 patients with heart failure of different severity admitted from March 2012 to December 2013 and divided into the death group and the survival group. The death group included patients with angina pectoris, recurrence of heart failure and the death cases, while the survival group did not include those with angina pectoris, recurrence of heart failure and death cases. And the changes of plasma concentration and prognosis were compared between the two groups. Results The result of the data analysis showed that for patients with different causes of disease, the plasma NT-proBNP concentrations were not the same. Compared with those without cardiovascular disease, patients with cardiovascular disease had lower left ventricular ejection fraction, with statistical significance（P〈0.05）. The data showed that the plasma concentration of patients in the death group on admission was significantly higher than that of those in the survival group. Conclusion The analysis of the data showed that the plasma concentration of the survival group was lower than that of the death group. If the plasma concentration in patients with heart failure continues to rise, the prognosis of the patients should be paid attention, which is of great research value in clinical practice.

关 键 词：心力衰竭 血浆浓度 变化分析 

分 类 号：R541.6[医药卫生—心血管疾病]