婴幼儿腹泻轮状病毒检测及结果分析  

Detection of Rotavirus in Infants with Diarrhea and Analysis of the Result

作　　者：袁野[1] 

机构地区：[1]重庆医科大学大学城医院,重庆401331

出　　处：《中外医疗》2015年第10期12-13,共2页China & Foreign Medical Treatment

摘　　要：目的：探讨婴幼儿腹泻轮状病毒的感染情况及其发病规律，为临床治疗提供依据。方法选取于2013年1—12月入该院就诊的腹泻婴幼儿2507例，收集其粪便标本采用乳胶法进行轮状病毒检测并对结果进行统计学分析。结果2507例送检标本中有393例轮状病毒抗原阳性，阳性率为15.68%。1～2岁婴幼儿轮状病毒检测阳性率为20.11%，6月龄～1岁婴幼儿检测阳性率为17.68%，均显著高于其他年龄段（P＜0.05）。其中1月收治腹泻婴幼儿178例，阳性45例，占25.28%；10月收治腹泻婴幼儿243例，阳性43例，占17.70%；11月收治腹泻婴幼儿224例，阳性77例，占34.38%；12月收治腹泻婴幼儿224例，阳性79例，占35.27%。其中11、12月阳性率明显高于其他月份（P＜0.05）。结论轮状病毒是引发婴幼儿腹泻的主要病原体，多发于6月龄～2岁婴幼儿，秋冬季节感染率较高，及时检测该病毒抗原可为疾病监测与临床治疗提供依据。Objective To investigate the infection of rotavirus in infants with diarrhea and the occurrence regularity of the disease so as to provide a basis for clinical treatment. Methods 2507 infants with diarrhea admitted in our hospital from January 2013 to December 2013 were selected. Emulsion technique was used to detect the rotavirus in the collected specimens of feces of the infants. And the results of detection were analyzed statistically. Results Of the 2507 specimens, there were 393 specimens with positive rotavirus antigen, the positive rate was 15.68%. The positive rate of rotavirus detection in 1~2 years old infants was 20.11%, and that in 6 months to 1 year old infants was 17.68%, much higher than that in the other age groups（P＆lt;0.05）. Among the 178 cases of infantile diarrhea treated in our department in January, 45 cases with positive rotavirus antigen, accounting for 25.28%;of the 243 cases with infantile diarrhea admitted in October, 43 cases with positive rotavirus antigen, accounting for 17.70%;of the 224 cases of infantile diarrhea admitted in November, 77 cases with positive rotavirus antigen, accounting for 34.38%;of the 224 cases of infantile diarrhea admitted in December, 79 cases with positive rotavirus antigen, accounting for 35.27%. The positive rate of rotavirus in November and December was much higher than that in the other months（P＆lt;0.05）. Conclusion Rotavirus is the main pathogen that causes infantile diarrhea. The disease frequently occurs in infants aged from 6 months to 2 years old, and the infection rate is higher in autumn and winter. Timely detection of the virus antigen can provide a basis for disease surveillance and clinical treatment.

关 键 词：婴幼儿 轮状病毒 腹泻 

分 类 号：R5[医药卫生—内科学]