地佐辛经硬膜外给药预防阑尾牵拉反应的临床研究  

The Study of Epidural Injection of Dezocine in Use of Preventing Visceral Reflex

作　　者：邓唯杰 

机构地区：[1]深圳市坪山新区人民医院麻醉科,广东深圳518118

出　　处：《中外医疗》2015年第11期91-92,95,共3页China & Foreign Medical Treatment

摘　　要：目的：研究地佐辛经硬膜外给药途径用于预防阑尾牵拉反应的疗效与不良反应。方法选择该院于2012年3月—2014年9月收治的阑尾切除术的患者44例，均符合美国麻醉医师分级（ASA）分级Ⅰ~Ⅱ级、术前检查无心肺相关疾病，随机数字表法分为硬膜外给药组（经硬膜外注射地左辛5 mg）和对照组静脉注射组（经静脉注射地左辛5 mg），观察术中患者阑尾牵拉的反应情况及相关不良反应。结果硬膜外和静脉注射组均达到了预防牵拉反应的良好效果，但硬膜外给药组RSS评分总体满意率高于静脉注射组（P〈0.05）；两组阑尾切除患者给药后脉搏氧饱和度（SPO2）及平均动脉压（MAP）差异无统计学意义（P〉0.05），但相关不良反应硬膜外给药组较静脉注射组少。结论地佐辛硬膜外相比较于对照组预防阑尾牵拉反应的效果更好，且硬膜外给药更安全、有效，嗜睡、恶心、呕吐等不良反应更少。ObjectiveTo study the clinical effects and side-effects of Epidural injection of Dezocine in use of preventing Visceral reflex.Methods In our hospital form 2012 March to 2014 Septenber Were treuted 44 cases of emergency appendectomy of ASA Ⅰ-Ⅱ were selected and randomly divided into two groups,group Epidural injection （ group A,n=22,injection with Dezocine 5mg） and group Intravenous injection（group B,n=22, injection with Dezocine 5mg）,Visceral reflex were observed and recorded.Results Both groups of Intravenous injection and Intravenous injection have well and similar effects in preventing visceraltraction,but the RSS of group Epidural injection was better（P〈0.05）, there was no significant difference between the observation group and the control group （P〉0.05） in MAP,SPO2,side-effects of Epidural injection were less observed.Conclusion Both groups of Intravenous injection and Intravenous injection have well and similar effects in preventing visceraltraction,but Epidural injection may be more safe and effective for it.

关 键 词：地佐辛 硬膜外给药 阑尾切除术 牵拉反应 

分 类 号：R4[医药卫生—临床医学]