蛛网膜下腔出血后脑血管痉挛发生机制的研究进展  

Related Research Progress on the Mechanisms of Cerebral Vasospasm after Subarachnoid Hemorrhage

作　　者：王宏瑜 毕云科[2] 刘耀华[2] 

机构地区：[1]鹤岗市人民医院神经外科,黑龙江鹤岗154100 [2]哈尔滨医科大学附属第一医院神经外科,哈尔滨150001

出　　处：《医学综述》2015年第10期1737-1740,共4页Medical Recapitulate

基　　金：国家自然科学基金(81172388)

摘　　要：蛛网膜下腔出血(SAH)是最常见的脑血管疾病之一。近年来,随着医疗水平的提高,动脉瘤经治疗后再出血的风险已很小,患者生存机会大大提高,但SAH后脑血管痉挛(CVS)的发生率却很高。预防和治疗SAH后CVS是神经外科医师面临的一个重大课题。氧合血红蛋白被广泛认为是SAH后致CVS各种原因中最重要的启动因素,而血管内皮细胞生长因子作为一种特异性内皮细胞有丝分裂原,对SAH后CVS发生有至关重要的作用,也是目前国内外研究CVS因素的热点。Subarachnoid hemorrhage （ SAH ） is one of the most common cerebrovascular diseases.In recent years,as the development of medical technology, the risk of re-hemorrhage is very small after treatment and the survival of patients are improved greatly,however the incidence of cerebral vasospasm（CVS） after SAH is high.The prevention and treatment of CVS after SAH is a major task of neuro-surgeons.Oxyhemo-globin is considered to be the most important initiating factor of CVS after SAH , and vascular endothelial growth factor also plays a crucial role in CVS,both of which are hotspots of research about CVS factors in and out of China.

关 键 词：蛛网膜下腔出血 脑血管痉挛 氧合血红蛋白 血管内皮细胞生长因子 

分 类 号：R446.11[医药卫生—诊断学]