体外循环和非体外循环下冠状动脉旁路移植术的疗效对比观察  

Observation and Comparison of the Curative Effect of Coronary Bypass Operation under Extracorporeal Circulation and Non-extracorporeal Circulation

作　　者：胡国智[1] 罗萍[1] 

机构地区：[1]武汉亚洲心脏病医院心外科,武汉430022

出　　处：《医学综述》2015年第10期1856-1857,共2页Medical Recapitulate

摘　　要：目的比较体外循环和非体外循环下冠状动脉旁路移植术的临床疗效和并发症。方法选择2012年2月至2014年5月在武汉亚洲心脏病医院行冠状动脉旁路移植术的70例患者作为研究对象,按照电脑产生的随机数列分为对照组和研究组,各35例。对照组患者在体外循环下进行手术,研究组在非体外循环下进行手术。比较两组患者临床疗效、客观指标情况(包括手术时间、输血量、住院时间、呼吸机辅助时间)和术后并发症。结果研究组治疗总有效率显著高于对照组[94.3%(33/35)比74.3%(26/35)],差异有统计学意义(P<0.05);研究组患者手术时间、术中输血量、住院时间、呼吸机辅助时间均较对照组显著缩短,差异均有统计学意义(均P<0.01);研究组术后并发症发生率显著低于对照组[17.1%(6/35)比42.9%(15/35)],差异有统计学意义(P<0.05)。结论冠状动脉旁路移植术在循环或非体外循环条件下均取得了一定的临床疗效,但在非体外循环下患者疗效更佳,既可做到创伤小、安全性高,又可避免术后并发症的出现,显著提高治疗有效率。Objective To compare the clinical curative effect of coronary bypass operation under extra-corporeal circulation and non-extracorporeal circulation.Methods A total of 70 patients underwent coronary artery bypass grafting in Wuhan Asia Heart Hospital from Feb .2012 to May 2014 were randomly divided into research group and control group,with 35 cases in each group.Patients in control group were treated with extracorporeal circulation,while patients in research group were treated with non-extracorporeal circulation. The clinical curative effect differences of objective indexes（including operation time,amount of blood transfu-sion,duration of hospital stay,respirator auxiliary time） and postoperative complications of the two groups were compared.Results The total effective rate of the research group was significantly higher than that of the control group [ 94 .3%（ 33/35 ） vs 74 .3%（ 26/35 ） ] , the difference was statistically significant （ P 〈0.05）.The operation time,amount of blood transfusion in operation,duration of hospital stay and respirator auxiliary time of the research group were significantly lower than the control group ,the differences were statis-tically significant（P〈0.01）.The incidence of postoperative complications of the research group was lower than that of the control group[17.1%（6/35） vs 42.9%（15/35）],the difference was statistically signifi-cant（P〈0.05）.Conclusion Coronary bypass operation either under extracorporeal circulation or under non-extracorporeal circulation can receive certain clinical curative effect ,while the clinical effect of operation under non-extracorporeal circulation is better,as it can ensure safety and minimal invasive as well as avoid postoperative complications and further improve the effective rate .

关 键 词：冠状动脉旁路移植术 体外循环 非体外循环 

分 类 号：R645[医药卫生—外科学]