艾可胶囊成型工艺的研究  

Studies on the Formulation process of Aike Capsules

作　　者：黄燕[1] 潘旭东[1] 沈小苹[1] 林雄[1] 

机构地区：[1]福建中医药大学附属人民医院,福州350004

出　　处：《海峡药学》2015年第5期21-23,共3页Strait Pharmaceutical Journal

基　　金：福建中医药大学临床类校管课题(XB2013006);福建科技计划项目(2013Y01010242)

摘　　要：目的探讨艾可胶囊成型工艺。方法考察不同辅料对浸膏粉吸湿性的影响,优选辅料并考察混合粉末的吸湿性、休止角、堆密度。结果艾可胶囊浸膏粉与乳糖的最佳比例为10∶4,休止角为36.11°,堆密度为0.62g·m L-1,临界相对湿度为63%。结论该成型工艺合理可行,适合于医院制剂的发展。OBJECTIVE To investigate the formulation procedure of Aike capsules.METHODS The influ-ence of different material to extract powder,hygroscopic,optimizing material and mixing the powder of hygroscopicity, Angle of repose and bulk density was investigated.RESULTS The optimal proportion of Aike capsules extract pow-der and lactose was 10∶4 with repose angle of 36.11＆#176;、pile density of 0.62g＆#183; mL-1 and the critical relative humidity of 63%.CONCLUSION The forming process is reasonable and feasible,suitable for the development of hospital preparations.

关 键 词：艾可胶囊 成型工艺 吸湿性 休止角 堆密度 

分 类 号：TQ460.4[化学工程—制药化工]