基于色素谱吸收原理的肝储备功能无创测量系统  

A method of non-invasive liver reserve function measurement based on pigment spectra absorption principle

作　　者：战荫泽[1] 秦颖[1] 张晶[1] 蔡靖[2] 戴强[2] 刘莉莉[3] 

机构地区：[1]长春理工大学光电信息学院,吉林长春130012 [2]吉林大学仪器科学与电气工程学院,吉林长春130012 [3]吉林大学第一医院,吉林长春130026

出　　处：《电子技术应用》2015年第6期59-61,65,共4页Application of Electronic Technique

摘　　要：肝病一直是我国高发疾病,肝储备功能是肝病诊治中重要的生理参数,医院传统方法采用采血比色法进行肝储备功能测量。利用吲哚氰绿ICG色素指示剂对805 nm波长光的吸光效应,患者注射ICG色素,分别采集0 min、5 min、10 min、15 min的血液样本,通过比色测量,绘制ICG浓度代谢曲线,测量肝储备功能。为了避免采血法对测量结果和病人的不良影响,提出基于色素谱吸收原理的无创肝储备功能测量系统的设计方案。实验证明,利用805 nm和940 nm敏感波长以及吲哚氰绿ICG色素吸光特性,能较好地实现无创肝储备功能测量。Liver disease has been the high incidence of disease in China, liver reserve function is an important physiological parameters in diagnosis and treatment of liver disease. Using blood colorimetfic method to measure liver reserve function traditionally in hospital, by indocyanine green ICG absorbing effect of 805 nm light. Patient is injected with ICG and drawed blood to measure ICG concentration in 0 minute, 5 minutes, 10 minutes and 15 minutes, achieve liver reserve function by plotting the ICG metabolism curve . In order to avoid the adverse effects of traditional liver reserve function measurement to the measurement results precision and patients health ,put forward the design scheme of non-invasive liver reserve function measurement system based on pigment spectra absorption light principle. Experiment result：by 805 nm ,940 nm spectrum properties and indocyanine green ICG dye absorp- tion light property to achieve non-invasive t of liver reserve function .

关 键 词：肝储备功能 色素谱吸光原理 无创检测 吲哚氰绿 

分 类 号：TP371.76[自动化与计算机技术—计算机系统结构]