犬多发性混合性乳腺瘤的特殊染色鉴别  

Differentiation of Multiple Mixed Mastadenoma in Dogs by Special Staining

作　　者：李瑞珍[1] 宋高杰[1] 赵俊江 梁莹莹[1] 郝军红[1] 苗盼盼[1] 潘耀谦[1] 

机构地区：[1]河南科技学院动物科学学院,河南新乡453003

出　　处：《动物医学进展》2015年第6期178-182,共5页Progress In Veterinary Medicine

基　　金：河南省科技攻关项目(132102110118)

摘　　要：为了鉴别犬多发性混合性乳腺瘤的形态结构及其发生的关系,用特殊染色法对两例肿瘤进行了详细的病理学观察及分析。结果表明,多发性混合性乳腺瘤组织中除了有单纯性乳腺瘤结构外,还包括乳头状瘤和囊腺瘤的结构,间质中有大量的结缔组织增生,形成条索状的胶原纤维束,增生的结缔化生形成了软骨组织。当乳腺瘤上皮增生过快时,可形成乳腺癌样的组织团块。研究表明,多发性混合性乳腺瘤可继发于单纯性乳腺瘤,是乳腺瘤加重的形态表现;混合性乳腺瘤组织的软骨组织是由结缔组织化生而来。由于多发性混合性乳腺瘤中有多种组织成分不断增生,并可出现乳腺癌样的组织团块,所以该瘤易于发生恶变。To identify the morphological structure and incidence relationship in multiple mixed mastadenoma of dogs, two tumor cases were observed and analyzed pathologically in detail by special staining. The re- suits revealed that in the tissues of multiple mixed mastadenoma, except for simple mastoncus structure, there were the structures of papilloma and cystadenoma, there were a mass of hyperplastic connective tis- sues in tumor mesenchyme, formed cord-like collagenous fiber and cartilaginous tissue by the metaplasia. Breast cancer-like block masses were examined in tumor tissue when the epithelia of breast tumor were rap- idly growing. In conclusion, multiple mixed mastadenoma might be secondary onset from simple mastade- noma and was an aggravating manifestation. Its cartilaginous tissue came from the metaplasia of connective tissue. Multiple mixed mastadenoma was apt to malignant transformation because there were a lot of con- tinuous proliferative cells and the breast cancer-like tissue masses were found in its tissues.

关 键 词：犬 混合性乳腺瘤 特殊染色 病理组织学 

分 类 号：S858.292[农业科学—临床兽医学] S857.26[农业科学—兽医学]